Drug design. Volume II / edited by E.J. Ariëns.
Drug Design, Volume II covers the design of bioactive compounds interacting with enzymes and playing a role in enzyme synthesis. The book discusses the modulation of pharmacokinetics by molecular manipulation; the factors in the design of reversible and irreversible enzyme inhibitors; and the design...
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| Online Access: |
Full Text (via ScienceDirect) |
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| Other Authors: | |
| Format: | eBook |
| Language: | English |
| Published: |
New York :
Academic Press,
1971.
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| Series: | Medicinal chemistry (Academic Press) ;
v. 11. |
| Subjects: |
| Summary: | Drug Design, Volume II covers the design of bioactive compounds interacting with enzymes and playing a role in enzyme synthesis. The book discusses the modulation of pharmacokinetics by molecular manipulation; the factors in the design of reversible and irreversible enzyme inhibitors; and the design of organophosphate and carbamate inhibitors of cholinesterases. The text also describes the design of reactivators for irreversibly blocked acetylcholinesterase; drug design based on the inhibition of protein synthesis in the context of susceptible enzymic reactions; as well as the role of enzymes. |
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| Physical Description: | 1 online resource : illustrations. |
| Bibliography: | Includes bibliographical references and indexes. |
| ISBN: | 9781483216041 1483216047 |
| Source of Description, Etc. Note: | Source of description: Print version record. |