Advances in asthma : pathophysiology, diagnosis and treatment / Akihito Yokoyama, editor.
This book provides discussions on bronchial asthma from a clinical perspective, focusing on the recent studies on its pathophysiology, diagnosis and treatment. It also explores the lastest findings regarding the phenotypes and endotypes of asthmatic patients, making it of particular interest to thos...
Saved in:
| Online Access: |
Full Text (via Springer) |
|---|---|
| Other Authors: | |
| Format: | eBook |
| Language: | English |
| Published: |
Singapore :
Springer,
[2019]
|
| Series: | Respiratory disease series.
|
| Subjects: |
MARC
| LEADER | 00000cam a2200000Mi 4500 | ||
|---|---|---|---|
| 001 | b10451197 | ||
| 006 | m o d | ||
| 007 | cr ||||||||||| | ||
| 008 | 181229s2019 si o 000 0 eng d | ||
| 005 | 20240423172357.6 | ||
| 010 | |a 2018964247 | ||
| 019 | |a 1080427505 |a 1086516852 |a 1088342203 |a 1105196272 |a 1118515554 |a 1122810916 |a 1129351908 |a 1135222308 |a 1156726378 |a 1162688829 | ||
| 020 | |a 9789811327902 |q (electronic bk.) | ||
| 020 | |a 9811327904 |q (electronic bk.) | ||
| 020 | |z 9789811327896 | ||
| 020 | |z 9811327890 | ||
| 024 | 7 | |a 10.1007/978-981-13-2790-2 | |
| 024 | 8 | |a 10.1007/978-981-13-2 | |
| 035 | |a (OCoLC)spr1080432081 | ||
| 035 | |a (OCoLC)1080432081 |z (OCoLC)1080427505 |z (OCoLC)1086516852 |z (OCoLC)1088342203 |z (OCoLC)1105196272 |z (OCoLC)1118515554 |z (OCoLC)1122810916 |z (OCoLC)1129351908 |z (OCoLC)1135222308 |z (OCoLC)1156726378 |z (OCoLC)1162688829 | ||
| 037 | |a spr978-981-13-2790-2 | ||
| 040 | |a EBLCP |b eng |e rda |e pn |c EBLCP |d GW5XE |d UAB |d OCLCF |d YDX |d LEAUB |d OH1 |d ESU |d UKMGB |d UKAHL |d LQU |d LEATE |d EBLCP |d OCLCQ |d VT2 |d OCLCA |d SRU | ||
| 049 | |a GWRE | ||
| 050 | 4 | |a RC591 |b .A38 2019 | |
| 245 | 0 | 0 | |a Advances in asthma : |b pathophysiology, diagnosis and treatment / |c Akihito Yokoyama, editor. |
| 264 | 1 | |a Singapore : |b Springer, |c [2019] | |
| 300 | |a 1 online resource (187 pages) | ||
| 336 | |a text |b txt |2 rdacontent. | ||
| 337 | |a computer |b c |2 rdamedia. | ||
| 338 | |a online resource |b cr |2 rdacarrier. | ||
| 347 | |a text file |b PDF |2 rda. | ||
| 490 | 1 | |a Respiratory Disease Series. | |
| 505 | 0 | |a Intro; Preface; Contents; Part I: Pathophysiology; Chapter 1: Genetics in Asthma; 1.1 Introduction; 1.2 Association Studies; 1.2.1 Candidate Gene Association Studies; 1.2.2 Genome-Wide Association Studies; 1.3 Phenotypic Heterogeneity, Epistasis, Gene-Environment Interactions, and Epigenetics; 1.4 Conclusion; References; Chapter 2: Group 2 Innate Lymphoid Cells and Asthma; 2.1 Introduction; 2.1.1 Two Distinct Type-2 Immune Responses; 2.1.2 Group 2 Innate Lymphoid Cells (ILC2s); 2.2 ILC2s in Patients with Asthma (Table 2.1) | |
| 505 | 8 | |a 2.2.1 ILC2s Are Increased in the Peripheral Blood and Airways of Patients with Asthma2.2.2 Increased ILC2 Numbers and Activation in More Severe Forms of Asthma; 2.2.3 ILC2s Are Increased in Eosinophilic Asthma; 2.3 Corticosteroid Sensitivity of ILC2s; 2.3.1 Corticosteroid Sensitivity of Murine and Human ILC2s; 2.3.2 Murine and Human ILC2s Isolated from Asthmatic Airways Are Corticosteroid-Resistant; 2.3.3 Mechanism of Corticosteroid Resistance Induction in Murine and Human ILC2s; 2.4 Asthma Exacerbation due to Viral Infection and ILC2s. | |
| 505 | 8 | |a 2.4.1 Airway IL-33/IL-25/TSLP Production During Viral Infection2.4.2 IL-33/IL-25/TSLP-Mediated Exacerbation of Airway Inflammation During Viral Infection; 2.4.3 IFN Response in Healthy and Asthmatic Airways During Viral Infection; 2.5 Conclusion; References; Chapter 3: Cellular Mechanisms of Allergic Airway Inflammation; 3.1 Introduction; 3.2 Airway Structural Cells; 3.2.1 Airway Epithelial Cells; 3.2.2 Airway Smooth Muscle Cells; 3.3 Innate and Adaptive Immune Cells; 3.3.1 Dendritic Cells (DCs) (Fig. 3.2); 3.3.2 CD4+ T cells; 3.3.2.1 Th2 Cells (Fig. 3.3); 3.3.2.2 Th1 Cells. | |
| 505 | 8 | |a 3.3.2.3 Th17 Cells3.3.2.4 Regulatory T cells (Tregs); 3.3.3 Group 2 Lymphoid Cell, Innate Lymphoid Cells (ILCs) (Fig. 3.3); 3.4 Conclusion; References; Chapter 4: Mechanisms for Non-eosinophilic Asthma; 4.1 Introduction; 4.2 Cellular Profiles of Eosinophilic and Non-eosinophilic Asthma; 4.3 Clinical Characteristics of Non-eosinophilic Asthma; 4.4 Evidence for Neutrophil Activation in Asthma; 4.5 Mechanisms of Eosinophilic and Non-eosinophilic Asthma; 4.5.1 Mechanisms of Neutrophilic Asthma; 4.5.2 Mechanisms of Paucigranulocytic Asthma. | |
| 504 | |a Includes bibliographical references. | ||
| 520 | |a This book provides discussions on bronchial asthma from a clinical perspective, focusing on the recent studies on its pathophysiology, diagnosis and treatment. It also explores the lastest findings regarding the phenotypes and endotypes of asthmatic patients, making it of particular interest to those involved with non-eosinophilic asthma and eosinophilic asthma. Further, it discusses the importance of ILC 2 in eosinophilic asthma, and the accumulated results from the forced oscilliation technique and periostin that are actively practiced in Japan. As some aspects of diagnosis and treatment are different in Western and Asian countries, it is important that the data is disseminated around the globe. The clinical questions addressed by the authors are critical and thought provoking, while the questions raised by the editors are instructive, informative and provide new perspectives on unresolved issues. This book appeals to wide readership from beginning learners to physicians in clinical practice and scholars engaging in basic research. | ||
| 588 | 0 | |a Print version record. | |
| 650 | 0 | |a Asthma. | |
| 650 | 0 | |a Asthma |x Treatment. | |
| 650 | 7 | |a Asthma. |2 fast |0 (OCoLC)fst00819313. | |
| 650 | 7 | |a Asthma |x Treatment. |2 fast |0 (OCoLC)fst00819329. | |
| 700 | 1 | |a Yokoyama, Akihito, |e editor. | |
| 776 | 0 | 8 | |i Print version: |a Yokoyama, Akihito. |t Advances in Asthma : Pathophysiology, Diagnosis and Treatment. |d Singapore : Springer, ©2018 |z 9789811327896 |w (OCoLC)1050614950. |
| 830 | 0 | |a Respiratory disease series. | |
| 856 | 4 | 0 | |u https://colorado.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-13-2790-2 |z Full Text (via Springer) |
| 907 | |a .b104511977 |b 11-22-21 |c 04-16-19 | ||
| 998 | |a web |b - - |c f |d b |e - |f eng |g si |h 0 |i 1 | ||
| 915 | |a M | ||
| 956 | |a Springer e-books | ||
| 956 | |b Springer Nature - Springer Medicine eBooks 2019 English International | ||
| 999 | f | f | |i 2d11d5d5-c5e7-5c9b-939d-a7cfae483e64 |s 2ad6269a-bd97-5af3-9093-f5fb28187446 |
| 952 | f | f | |p Can circulate |a University of Colorado Boulder |b Online |c Online |d Online |e RC591 .A38 2019 |h Library of Congress classification |i Ebooks, Prospector |n 1 |