Integrins [electronic resource] / edited by David Cheresh.

An integrin, or integrin receptor, is an integral membrane protein in the plasma membrane of cells. It plays a role in the attachment of a cell to the extracellular matrix (ECM) and to other cells, and in signal transduction from the ECM to the cell. There are many types of integrin, and many cells...

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Bibliographic Details
Online Access: Full Text (via ScienceDirect)
Other Authors: Cheresh, David A.
Format: Electronic eBook
Language:English
Published: San Diego, Calif. : Elsevier Academic Press, ©2007.
Series:Methods in enzymology ; v. 426.
Subjects:

MARC

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260 |a San Diego, Calif. :  |b Elsevier Academic Press,  |c ©2007. 
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490 1 |a Methods in enzymology,  |x 0076-6879 ;  |v v. 426. 
504 |a Includes bibliographical references and index. 
505 0 0 |g Chapter 1.  |t Quantitative measurements of integrin-mediated adhesion to extracellular matrix /  |r David Boettiger --  |g Chapter 2.  |t Investigating integrin regulation and signaling events in three dimensional systems /  |r Patricia J. Keely [and others] --  |g Chapter 3.  |t Integrins in cell migration /  |r Keefe T. Chan, Christa L. Cortesio, and Anna Huttenlocher --  |g Chapter 4.  |t Integrin cytoskeletal interactions /  |r Yatish Lad, David S. Harburger, and David A. Calderwood --  |g Chapter 5.  |t Cell survival in a 3D matrix /  |r Alireza Alavi and Dwayne G. Stupack --  |g Chapter 6.  |t Platelet integrin adhesive functions and signaling /  |r Nicolas Prévost [and others] --  |g Chapter 7.  |t Development of monoclonal antibodies to integrin receptors /  |r E. A. Wayner and B. G. Hoffstrom --  |g Chapter 8.  |t Cell adhesion, cellular tension, and cell cycle control /  |r Eric A. Klein [and others] --  |g Chapter 9.  |t Analysis of integrin signaling by fluorescence resonance energy transfer /  |r Yingxiao Wang and Shu Chien --  |g Chapter 10.  |t Studies on integrins in the nervous system /  |r Sumiko Denda and Louis F. Reichardt. 
505 8 0 |g Chapter 11.  |t Methods for identifying novel integrin ligands /  |r Denise K. Marciano, Sumiko Denda, and Louis F. Reichardt --  |g Chapter 12.  |t Analysis of integrin functions in peri-implantation embryos, hematopoietic system and skin /  |r Eloi Montanez [and others] --  |g Chapter 13.  |t Identification and molecular characterization of multiple phenotypes in integrin knockout mice /  |r Chun Chen and Dean Sheppard --  |g Chapter 14.  |t Purification, analysis and crystal structure of integrins /  |r Jian-Ping Xiong, Simon L. Goodman, and M. Amin Arnaout --  |g Chapter 15.  |t Electron microscopy of integrins /  |r Brian D. Adair and Mark Yeager --  |g Chapter 16.  |t Intravital imaging and cell invasion /  |r Milan Makale --  |g Chapter 17.  |t Using xenopus embryos to investigate integrin function /  |r Douglas W. DeSimone, Bette Dzamba, and Lance A. Davidson --  |g Chapter 18.  |t Methods to study lymphatic vessel integrins /  |r Barbara Garmy-Susini [and others] --  |g Chapter 19.  |t Analysis of integrin signaling in genetically engineered mouse models of mammary tumor progression /  |r Yuliyz Pylayeva, Wenjun Guo, and Filippo G. Giancotti --  |g Chapter 20.  |t Design and chemical synthesis of integrin ligands /  |r Dominik Heckmann and Horst Kessler --  |g Chapter 21  |t Evaluating integrin function in models of angiogenesis and vascular permeability /  |r Sara M. Weis. 
520 |a An integrin, or integrin receptor, is an integral membrane protein in the plasma membrane of cells. It plays a role in the attachment of a cell to the extracellular matrix (ECM) and to other cells, and in signal transduction from the ECM to the cell. There are many types of integrin, and many cells have multiple types on their surface. Integrins are of vital importance to all metazoans, from humans to sponges. This volume in Methods in Enzymology presents methods for studying integrins. 
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