Zebrafish / volume editor, Steve F. Perry [and others]

This cutting-edge resource includes up-to-date information on zebrafish physiology and the tools used to study it, not only as a model species for studies of other vertebrates but with application for studies of human disease and aquatic toxicology. The utility of zebrafish for physiological researc...

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Bibliographic Details
Online Access: Full Text (via ScienceDirect)
Other Authors: Perry, Steve F., 1955-
Other title:Elsevier life sciences books series.
Format: eBook
Language:English
Published: Amsterdam : Academic, [2010]
Edition:1st ed.
Series:Fish physiology ; v. 29.
Subjects:
Table of Contents:
  • FRONT COVER; ZEBRAFISH; COPYRIGHT PAGE; CONTENTS; CONTRIBUTORS; PREFACE; Chapter 1. Genetic Tools; 1. Introduction; 2. Forward Genetics: From Large Screens to Targeted Screens; 3. Reverse Genetics: Morpholino Knockdowns; 4. Reverse Genetics: TILLING; 5. Reverse Genetics: Zinc Finger Nucleases; 6. Gain of Function: Targeted Misexpression of Genes; 7. Genetic Ablation of Specific Cell Population; 8. Concluding Remarks; Chapter 2. Organization and Physiology of the Zebrafish Nervous System; 1. Introduction; 2. Nervous System Development and General Organization.
  • 3. General Organization of the Zebrafish Nervous System, Subdivisions and Main Functions4. The Peripheral Nervous System; 5. Sensory Systems; 6. Motor Systems and Integrative Centers; 7. Monoaminergic and Related Regulatory Systems; 8. Emotions and Cognition; 9. Nervous System Plasticity; Chapter 3. Zebrafish Vision: Structure and Function of the Zebrafish Visual System; 1. Visual Ecology; 2. Structure of the Visual System; 3. Retinal Projections; 4. Optic Tectum; 5. Visual Behavior; 6. Complex Visual Behavior; 7. Concluding Remarks; Chapter 4. The Zebrafish Inner Ear; 1. Introduction.
  • 2. Development of the Inner Ear3. Generation and Homeostasis of Endolymph in the Zebrafish Inner Ear; 4. Zebrafish Sensory Hair Cells; 5. Mechanotransduction; 6. Neural Activity; 7. Otoliths; 8. Adult Hearing; 9. Concluding Remarks; Chapter 5. Endocrinology of Zebrafish: A Small Fish with a Large Gene Pool; 1. Introduction; 2. Reproduction; 3. Stress: The Cortisol Stress Axis; 4. Growth; 5. Thyroidal Regulation; 6. Energy Homeostasis: Food Intake and Metabolism; 7. Osmoregulation; 8. Summary; Chapter 6. Developmental Physiology of the Zebrafish Cardiovascular System.
  • 1. Cardiovascular Disease: Models Wanted2. Current Models for Cardiovascular System Studies; 3. Filling a Niche with Zebrafish; 4. Unique Advantages of the Zebrafish for Cardiovascular Studies; 5. Vertebrate Cardiac Development; 6. Origin and Lineage of Cells in the Cardiovascular System; 7. Zebrafish Genetics and Development of the Cardiovascular System; 8. Genetic Infrastructure and Tools for Zebrafish Studies; 9. Zebrafish Cardiovascular Mutants; 10. Mutants Affecting Rate, Rhythm and Contractile Properties of the Heart; 11. Relationship Between Cardiovascular Function and Form.
  • 12. Endothelial Cell Specification and Differentiation13. Specification of Artery and Vein; 14. Cell Migration of Angioblasts and Vascular Patterning; 15. Angiogenesis of the Intersegmental Vessels; 16. Lumenization of Vessels; 17. Vascular Stabilization, Mural Cells, and Extracellular Matrix; 18. Angiogenesis of Organs; 19. Chemical Biology Approaches to Study Cardiovascular Biology; 20. Forces that Influence Cardiovascular Development; 21. Endothelial Cell Survival; 22. Zebrafish Models for Vascular Anomalies; 23. Tools for the Study of Cardiovascular Physiology; 24. Vessel Regeneration.