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035 |a (TOE)ost1651183 
035 |a (TOE)1651183 
040 |a TOE  |c TOE 
049 |a GDWR 
086 0 |a E 1.99:doe-zettar-19680 
086 0 |a E 1.99:doe-zettar-19680 
088 |a doe-zettar-19680 
245 0 0 |a Boost the biopharmaceutical industry?s research efficiency with hyperscale data distribution  |h [electronic resource] 
260 |a Washington, D.C. :  |b United States. Department of Energy. Office of Science ;  |a Oak Ridge, Tenn. :  |b Distributed by the Office of Scientific and Technical Information, U.S. Department of Energy,  |c 2020. 
300 |a Medium: ED :  |b digital, PDF file. 
336 |a text  |b txt  |2 rdacontent. 
337 |a computer  |b c  |2 rdamedia. 
338 |a online resource  |b cr  |2 rdacarrier. 
500 |a Published through Scitech Connect. 
500 |a 08/27/2020. 
500 |a "doe-zettar-19680." 
500 |a Fang, Chin  
500 |a Zettar Inc. 
520 3 |a The biopharmaceutical industry is facing fast growing data movement challenges, e.g. the latest powerful genome sequencers can spit out multiple TBs of data in each run; in an active lab, the amount of personalized medicine research data is growing by multiple TBs/day. The large entities of the industry are often distributed, even global in nature. Multi-site collaboration is mandatory to make research progress. These, plus other needs, such as disaster recovery, make the problems even more acute. The existing data transfer solutions, both commercial and free, have shown to be woefully inadequate. So a new way of thinking and doing becomes mandatory. Zettar has introduced a hyperscale data distribution software platform which has conclusively shown in the environment of a large global biotech company to be superior to all existing data transfer solutions in terms of performance, ease-of-use, robustness, and scalability. The Phase I proposed two non- incremental innovations. The outcome of the effort clearly shows the final product will be valuable to all the distributed data-intensive industries. During Phase I, Zettar conducted research in 1) Parallel streaming, integrating new results with reference data in real time at very high-speed, and 2) A machine-learning (ML) based approach to optimize any data transfer set up. This helps manage data across distributed environments and/or heterogeneous architectures. The project will enable and facilitate nearly real-time analysis even when petascale data sets must be employed in a distributed manner. For example, this is valuable in the effective and efficient use of output data from modern sequencing machines and electron-microscopy devices, among others. 
536 |b SC0019680. 
650 7 |a 97 mathematics and computing  |2 local. 
650 7 |a Distributed environments  |2 local. 
650 7 |a Work-fow acceleration  |2 local. 
650 7 |a Bigdata  |2 local. 
650 7 |a Hyperscale data distribution  |2 local. 
650 7 |a Data transfer  |2 local. 
650 7 |a Real time data analysis, data management  |2 local. 
650 7 |a Scale-out  |2 local. 
650 7 |a Peer-to-peer  |2 local. 
650 7 |a Highly available  |2 local. 
650 7 |a Distributed data-intensive enterprises  |2 local. 
650 7 |a It infrastructure cost-saving  |2 local. 
650 7 |a It infrastructure roi  |2 local. 
650 7 |a Multiscale 3d and 4d images  |2 local. 
650 7 |a Sequencers  |2 local. 
650 7 |a Large-scale, multimodal and multiscale data  |2 local. 
650 7 |a Advanced imaging devices, petabytes, exabytes  |2 local. 
650 7 |a Data integration  |2 local. 
650 7 |a Software framework  |2 local. 
710 2 |a United States. Department of Energy. Office of Science.  |4 spn. 
710 1 |a United States.  |b Department of Energy.  |b Office of Scientific and Technical Information  |4 dst. 
856 4 0 |u http://www.osti.gov/servlets/purl/1651183  |z Full Text (via OSTI) 
907 |a .b114520094  |b 11-30-21  |c 10-05-20 
998 |a web  |b 12-07-20  |c f  |d m   |e p  |f eng  |g    |h 0  |i 2 
956 |a Information bridge 
999 f f |i 2aebf395-2626-57c0-80e7-ccb3098ace7c  |s be8cc77d-795b-5cff-82a1-eab4ac22574c 
952 f f |p Can circulate  |a University of Colorado Boulder  |b Online  |c Online  |d Online  |e E 1.99:doe-zettar-19680  |h Superintendent of Documents classification  |i web  |n 1