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|a GWRE
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4 |
|a TP248.25.B55
|b H67 2006eb
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| 100 |
1 |
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|a Hochfeld, William L.
|0 http://id.loc.gov/authorities/names/n95003266
|1 http://isni.org/isni/0000000035299859.
|
| 245 |
1 |
0 |
|a Producing biomolecular substances with fermenters, bioreactors, and biomolecular synthesizers
|h [electronic resource] /
|c William L. Hochfeld.
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| 260 |
|
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|a Boca Raton, FL :
|b CRC/Taylor & Francis,
|c 2006.
|
| 300 |
|
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|a 1 online resource (383 pages) :
|b illustrations.
|
| 336 |
|
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|a text
|b txt
|2 rdacontent.
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| 337 |
|
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|a computer
|b c
|2 rdamedia.
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| 338 |
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|a online resource
|b cr
|2 rdacarrier.
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| 504 |
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|a Includes bibliographical references (pages 357-372) and index.
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| 505 |
0 |
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|a Introduction ; Biotechnology; Bioproduction; The Bioprocess; Cell Lines; Cell-Culture Process; Separation, Recovery,
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| 505 |
0 |
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|a Purification; Virus and Foreign-DNA Removal; Quality Assurance; Technology Overview ; Biomolecular Foundations; Cellular Variation; Key Molecular Interactions; Base-Pair Complementarity; Genetic Coding; Interrupting Gene Segments; Sequence Determinations; Cloning; Synthesized DNA; Cell Lines; Expression Systems Introduction to the Bioprocess ; Overview; Optimizing Product Yield; Kinetic Models; cGMP Standards; Contract Manufacturing; Complex Mixtures; Biomolecular Products; Joint Manufacturing; Downscaling to Scale Up; Large-Scale Bioprocesses; Scaling-Up In-House or in a Contract Facility; Lab-to-Pilot-Plant-to-Production; Increasing Bioprocess Scale; Differing Features at Larger Scale; Simulating Environment at Scale; Detailed Specifications; Impact on Downstream Bioprocessing; FDA Biologics Review Process.
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| 505 |
0 |
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|a ; Regulating Biological Products Recombinant DNA Materials and Methods ; Cloning; Applications; Screening and Selection; DNA Synthesis; Cell Lines; Expression Systems; Vector Construction; Prokaryotic and Eukaryotic Growth Characteristics; Expression Levels; Intra- vs.
|
| 505 |
0 |
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|a Extra-cellular Expression; Intracellular Expression; Extracellular Expression; Glycosylation; Mammalian Cell Glycosylation; Insect Cell Glycosylation; General Considerations; Further Post-translational Modifications; Economic Concerns; Regulatory Concerns; Manufacturers' Directory Enzymes ; Overview; Enzyme Protein Engineering; Transformation in Non-Aqueous Systems; Restriction Enzymes; Restriction-Enzyme Classes; Class I Restriction Enzymes; Class II Restriction Enzymes; Class III Restriction Enzymes; Restriction-Enzyme Specificity; Star Activity; Enzyme Families and Compatible Ends; Isoschizomers; Reverse Transcriptases; DNA and RNA Nucleases; Manufacturers' Directory DNA-Amplification Reagents ; Overview; Amplification by DNA Synthesis (PCR); Amplification by RNA Transcription (TAS and 3SR; Amplification by Ligation (LAR, LCR,
|
| 505 |
0 |
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|a LAS); Amplification by RNA Replication (Q Replicase); Sequence-Based Amplification; Manufacturers Directory Cell-Culture Media ; Overview; Prokaryotic Cell-Culture Medium; Eukaryotic Cell-Culture Medium; Defined Medium; Serum; Other Sera; Serum Contamination; Serum-Free (Defined) Medium; Cell-Culture Gels; Media Supplements; Attachment Factors; Buffers; Sodium; Earle's Balanced Salt Solution; Growth Factors; Epidermal Growth Factor (EGF); Fibroblast Growth Factors (FGF); Acidic FGF; Basic FGF; Other Growth Factors; Lectins; Toxins; Transport Factors; Vitamins; Water; Manufacturers' Directory Fermenters ; Introduction to Fermentation; Historical Perspective; The Fermentation Process; Enzyme Fermentation in the Organic Phase; Cell Growth and Production; Factors Affecting Specific Growth Rate; Kinetic.
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| 505 |
0 |
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|a Models; Optimal Conditions; Recombinant Culture Kinetics; Fermenter Design; Kinetic Modeling of the Fermentation Process; STF Batch Scale Up; Power Number Method for STF Geometric Scale Up; Continuous-Culture Scale Up; Fermenter Manufacturers Directory Bioreactors ; Introduction; Aseptic Conditions; Monoclonal Antibody Production; mAB Production in Ascites Fluid; Bioreactor Engineering and Design; Bioreactors II: Kinetic Modeling and Bioreactor Dynamics and Bioreactor Design Program; Bioreactor Manufacturers Directory Biomolecular Synthesizers ; DNA Synthesizers; Manufacturers Directory; Technology Overview; Peptides by Solid-Phase Synthesis; Manufacturers Directory; Biotechnology Glossary ; References and Recommended Reading Index.
|
| 588 |
0 |
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|a Print version record.
|
| 650 |
|
0 |
|a Biomolecules
|x Synthesis.
|
| 650 |
|
0 |
|a Bioreactors.
|0 http://id.loc.gov/authorities/subjects/sh87005835.
|
| 650 |
|
7 |
|a Biomolecules
|x Synthesis.
|2 fast
|0 (OCoLC)fst01424701.
|
| 650 |
|
7 |
|a Bioreactors.
|2 fast
|0 (OCoLC)fst00832686.
|
| 730 |
0 |
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|a BIOSCIENCEnetBASE.
|
| 776 |
0 |
8 |
|i Print version:
|a Hochfeld, William L.
|t Producing biomolecular substances with fermenters, bioreactors, and biomolecular synthesizers.
|d Boca Raton, FL : CRC/Taylor & Francis, 2006
|z 0849322707
|z 9780849322709
|w (DLC) 2005050643
|w (OCoLC)60776869.
|
| 856 |
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0 |
|u https://colorado.idm.oclc.org/login?url=https://www.taylorfrancis.com/books/9780429117398
|z Full Text (via Taylor & Francis)
|
| 907 |
|
|
|a .b115402731
|b 10-19-21
|c 01-22-21
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|b 04-12-21
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|a .b115402731
|b 04-12-21
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| 944 |
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|a MARS - RDA ENRICHED
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|p Can circulate
|a University of Colorado Boulder
|b Online
|c Online
|d Online
|e TP248.25.B55 H67 2006eb
|h Library of Congress classification
|i web
|n 1
|
