Molecular diagnostics : the key driver in personalized cancer medicine / editors, Jan Trost Jorgensen, Henrik Winther.
Provides an overview of molecular cancer diagnostic assays, which are the prerequisites for optimal solutions within personalized cancer medicine. This book offers definitions of the pharmacodiagnostic concept, and historical perspectives of the early steps into molecular cancer diagnostics linked t...
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Full Text (via Taylor & Francis) |
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| Format: | eBook |
| Language: | English |
| Published: |
Singapore :
Pan Stanford Pub.,
©2010.
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MARC
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| 245 | 0 | 0 | |a Molecular diagnostics : |b the key driver in personalized cancer medicine / |c editors, Jan Trost Jorgensen, Henrik Winther. |
| 260 | |a Singapore : |b Pan Stanford Pub., |c ©2010. | ||
| 300 | |a 1 online resource (x, 351 pages) : |b illustrations. | ||
| 336 | |a text |b txt |2 rdacontent. | ||
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| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Introduction / Jan Trs?t Jr?gensen and Henrik Winther -- Developing molecular diagnostics in cancer / Henrik Winther and Jan Trs?t Jr?gensen -- The estrogen and progesterone receptors : setting the scene for pharmacodiagnostics / Kwok-Leung Cheung -- The development of the HercepTest : from bench to bedside / Jan Trs?t Jr?gensen and Henrik Winther -- Predictive biomarkers and translational cancer medicine / Anne-Sofie Schrohl [and others] -- Pharmacodiagnostic testing : immunohistology / Anthony S.-Y. Leong and Trishe Y.-M. Leong -- In situ hybridisation for pharmacodiagnostic testing / John M.S. Bartlett and Fiona M. Campbell -- MammaPrint translating research into a diagnostic test / Annuska M. Glas, Leonie Delahaye and Oscar Krijgsman -- DNA biomarkers in the diagnosis and management of cancer / Reza Rafiolsadat Serizawa and Per Guldberg -- Validating the analytical power and parameters of an immunohistochemical test / Sr?en Nielsen -- Drug and pharmacodiagnostic co-development : statistical considerations / Richard Simon -- Clinical validation of biomarkers in cancer / Sumithra J. Mandrekar and Daniel J. Sargent -- Pharmacogenomic markers for cancer therapy / Sharon Marsh -- Safety and effective biomakers in oncology : a regulatory drug and device perspective / Atiqur Rahman and Francis Kalush -- Personalizing treatment selection for breast cancer / Lajos Pusztai and Chit Cheng Yeoh -- Pharmacodiagnostics and personalized medicine in cancer / Jan Trs?t Jr?gensen. | |
| 520 | |a Provides an overview of molecular cancer diagnostic assays, which are the prerequisites for optimal solutions within personalized cancer medicine. This book offers definitions of the pharmacodiagnostic concept, and historical perspectives of the early steps into molecular cancer diagnostics linked to therapy. | ||
| 545 | 0 | |a Dr Jan Trost Jorgensen holds an MSc degree in pharmacy and a PhD in clinical pharmacy from the Faculty of Pharmaceutical Sciences, University of Copenhagen. He has worked with drug development in biotech and pharmaceutical companies for more than 25 years, and within the last 10 years his focus has been on drug-diagnostic co-development projects within cancer. Dr Jorgensen is a strong supporter of more individualized pharmacotherapy and has published a number of scientific papers on oncology as well as on stratified and personalized medicine. | |
| 588 | 0 | |a Print version record. | |
| 650 | 0 | |a Molecular diagnosis. |0 http://id.loc.gov/authorities/subjects/sh93001015. | |
| 650 | 0 | |a Genetic screening. |0 http://id.loc.gov/authorities/subjects/sh99000370. | |
| 650 | 7 | |a Genetic screening. |2 fast |0 (OCoLC)fst00940094. | |
| 650 | 7 | |a Molecular diagnosis. |2 fast |0 (OCoLC)fst01024777. | |
| 700 | 1 | |a Jørgensen, Jan Trøst. |0 http://id.loc.gov/authorities/names/nb2010017679 |1 http://isni.org/isni/0000000117813567. | |
| 700 | 1 | |a Winther, Henrik. |0 http://id.loc.gov/authorities/names/nb2010017680 |1 http://isni.org/isni/0000000117328350. | |
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