Handbook of mitochondrial dysfunction / edited by Shamim I. Ahmad.
Mitochondria produce the chemical energy necessary for eukaryotic cell functions; hence mitochondria are an essential component of health, playing roles in both disease and aging. More than 80 human diseases and syndromes are associated with mitochondrial dysfunction; this book focuses upon diseases...
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Format: | eBook |
Language: | English |
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Boca Raton, FL :
CRC Press,
[2019]
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Table of Contents:
- SECTION I: Introduction: structure and function of mitochondria
- Mitochondrial structure and function
- Structure, function and evolutionary aspects of mitochondria
- Mitochondrial genome damage, dysfunction and repair
- SECTION II: Mitochondrial dysfunction and diseases
- Instability of human mitochondrial DNA, nuclear genes and diseases
- Kearns-Sayre syndrome
- Mitochondrial dysfunction and Barth Syndrome
- Mitochondrial dysfunction in the pathophysiology of Alzheimer's disease
- Mitochondrial dysfunction in multiple sclerosis
- Mitochondrial dysfunction in chronic kidney disease
- Mitochondrial dysfunction in breast cancer: a potential target from the bench to clinical therapeutics
- Mitochondrial dysfunction and DNA methylation in atherosclerosis
- Mitochondrial dysfunction and heart diseases
- The roles of mitochondrial dysfunction in mitophagy and apoptosis and its relevance to cancer
- Mitochondrial dysfunction linking obesity and asthma
- Mitochondrial dysfunction and hearing loss
- Superoxide dismutase, mitochondrial dysfunction, and neurodegenerative diseases
- Role of post-translational modifications of mitochondrial complex I in mitochondrial dysfunction and human brain pathologies
- Heme oxygenase-1 in kidney health and disease: perspective of mitochondrial homeostasis
- Mitochondrial transplantation in myocardial ischemia and reperfusion injury
- Mitochondrial dysfunction in diabetes
- Clinical manifestation of mitochondrial disorders in childhood
- Mitochondrial dysfunction and epilepsies
- Mitochondrial dysfunction and allergic disease.
- SECTION III: Factors affecting mitochondrial function
- Role of carnosic acid in protection of brain mitochondria
- Mitochondrial dysfunction and its impact on oxidative capacity of muscle
- The effects of resveratrol on the brain mitochondria
- Pathophysiology and biomarkers of mitochondrial dysfunction induced by heavy exercise
- Mitochondrial pathologies and their neuro muscular manifestations
- Mitochondrial stress and cellular senescence
- Role of mitochondrial dysfunction in human obesity
- Roles of melatonin in maintaining mitochondrial welfare: focus on renal cells
- Mitochondrial dysfunction affecting the peripheral nervous system in diabetic neuropathy and avenues for therapy
- Mitochondrial dysfunction and oxidative stress in the pathogenesis of metabolic syndrome
- SECTION IV: Immunity and toxicity
- Regulation of antiviral immunity by mitochondrial dynamics
- Mitochondrial dysfunction, immune systems, their diseases, and possible treatments
- Organophosphorus compound-induced mitochondrial disruption
- Itochondrial dysfunction in Friedreich Ataxia
- Index.