Handbook of mitochondrial dysfunction / edited by Shamim I. Ahmad.

Mitochondria produce the chemical energy necessary for eukaryotic cell functions; hence mitochondria are an essential component of health, playing roles in both disease and aging. More than 80 human diseases and syndromes are associated with mitochondrial dysfunction; this book focuses upon diseases...

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Bibliographic Details
Online Access: Full Text (via Taylor & Francis)
Other Authors: Ahmad, Shamim I.
Format: eBook
Language:English
Published: Boca Raton, FL : CRC Press, [2019]
Subjects:
Table of Contents:
  • SECTION I: Introduction: structure and function of mitochondria
  • Mitochondrial structure and function
  • Structure, function and evolutionary aspects of mitochondria
  • Mitochondrial genome damage, dysfunction and repair
  • SECTION II: Mitochondrial dysfunction and diseases
  • Instability of human mitochondrial DNA, nuclear genes and diseases
  • Kearns-Sayre syndrome
  • Mitochondrial dysfunction and Barth Syndrome
  • Mitochondrial dysfunction in the pathophysiology of Alzheimer's disease
  • Mitochondrial dysfunction in multiple sclerosis
  • Mitochondrial dysfunction in chronic kidney disease
  • Mitochondrial dysfunction in breast cancer: a potential target from the bench to clinical therapeutics
  • Mitochondrial dysfunction and DNA methylation in atherosclerosis
  • Mitochondrial dysfunction and heart diseases
  • The roles of mitochondrial dysfunction in mitophagy and apoptosis and its relevance to cancer
  • Mitochondrial dysfunction linking obesity and asthma
  • Mitochondrial dysfunction and hearing loss
  • Superoxide dismutase, mitochondrial dysfunction, and neurodegenerative diseases
  • Role of post-translational modifications of mitochondrial complex I in mitochondrial dysfunction and human brain pathologies
  • Heme oxygenase-1 in kidney health and disease: perspective of mitochondrial homeostasis
  • Mitochondrial transplantation in myocardial ischemia and reperfusion injury
  • Mitochondrial dysfunction in diabetes
  • Clinical manifestation of mitochondrial disorders in childhood
  • Mitochondrial dysfunction and epilepsies
  • Mitochondrial dysfunction and allergic disease.
  • SECTION III: Factors affecting mitochondrial function
  • Role of carnosic acid in protection of brain mitochondria
  • Mitochondrial dysfunction and its impact on oxidative capacity of muscle
  • The effects of resveratrol on the brain mitochondria
  • Pathophysiology and biomarkers of mitochondrial dysfunction induced by heavy exercise
  • Mitochondrial pathologies and their neuro muscular manifestations
  • Mitochondrial stress and cellular senescence
  • Role of mitochondrial dysfunction in human obesity
  • Roles of melatonin in maintaining mitochondrial welfare: focus on renal cells
  • Mitochondrial dysfunction affecting the peripheral nervous system in diabetic neuropathy and avenues for therapy
  • Mitochondrial dysfunction and oxidative stress in the pathogenesis of metabolic syndrome
  • SECTION IV: Immunity and toxicity
  • Regulation of antiviral immunity by mitochondrial dynamics
  • Mitochondrial dysfunction, immune systems, their diseases, and possible treatments
  • Organophosphorus compound-induced mitochondrial disruption
  • Itochondrial dysfunction in Friedreich Ataxia
  • Index.