Endotoxin in health and disease / edited by Helmut Brade [and three others]
Offering a basis for further research into the interactions of hosts and pathogens, this work gathers up-to-date findings, and details basic structures, functions and immunology. It provides descriptions of a variety of experimental endotoxin neutralizing agents, as well as a guide to clinical resea...
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Online Access: |
Full Text (via Taylor & Francis) |
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Format: | eBook |
Language: | English |
Published: |
Boca Raton :
CRC Press,
2020.
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Subjects: |
MARC
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245 | 0 | 0 | |a Endotoxin in health and disease / |c edited by Helmut Brade [and three others] |
264 | 1 | |a Boca Raton : |b CRC Press, |c 2020. | |
300 | |a 1 online resource. | ||
336 | |a text |b txt |2 rdacontent. | ||
337 | |a computer |b c |2 rdamedia. | ||
338 | |a online resource |b cr |2 rdacarrier. | ||
500 | |a Originally published: New York: Marcel Dekker, 1999. | ||
504 | |a Includes bibliographical references. | ||
505 | 0 | |a Endotoxin -- historical perspectives; lipopolysaccharide and the permeability of the bacterial outer membrane; lypopolysacharide phase variation in haemophilus and neisseria; antigenic mimicry in neisseris spp; antibiotic-induced endotoxin release -- important parameters dictating responses; complement-mediated lipopolysaccharide release; chemical structure of lipid A -- recent advances in structural analysis of biologically active molecules; chemical structure of the core region of lipopolysaccharides; the chemistry of O-polysacharide chains in bacterial lipopolysaccharides; the chemistry and biology of lipooligosacharides -- the endotoxins of bacteria of the respiratory and genital mucosae; a biophysical view on the function and activity of endotoxins; lipopolysaccharide preparations in aqueous media -implications for solution versus suspension; chlamydia lipopolysaccharides; chemical synthesis of lipid A; chemical synthesis of core structures; microbial pathways of lipid A biosynthesis; biosynthesis and genetics of lipopolysaccharides core; genetics and biosynthesis of lipopolysacchrides O-antigens; lipopolysaccharide-binding protein; bactericidal/permeability-increasing protein, P15s and phospholipases A2, endogenous antibiotics in host defense against bacterial infection; interactions of lipopolysacharides and lipoproteins; effects of human haemoglobin on bacterial endotoxin in vitro and in vivo; LPS/lipid A binding synthetic peptides; interaction of lipid A and lipopolysaccharide with human serum albumin; endothelial cell activation by lipopolysaccharide -- role of soluble CD14; scavenger receptor and lipopolysaccharide -- the role of platelet-activating factor; CD14, an innate immune receptor for various bacterial cell wall components; the role of MAP kinases, phosphatidylinositol 3-kinase and ceramide in LPS-induced signalling in macrophages; endotoxin effects on synthesis of phosphatidic acid and phosphatidic acid-derived diacylglyceride species. (Part contents) | |
520 | |a Offering a basis for further research into the interactions of hosts and pathogens, this work gathers up-to-date findings, and details basic structures, functions and immunology. It provides descriptions of a variety of experimental endotoxin neutralizing agents, as well as a guide to clinical research initiatives and the latest treatments. | ||
545 | 0 | |a Helmut Brade. | |
650 | 0 | |a Endotoxins. |0 http://id.loc.gov/authorities/subjects/sh85043104. | |
650 | 7 | |a Endotoxins. |2 fast |0 (OCoLC)fst00909841. | |
700 | 1 | |a Brade, Helmut, |d 1948- |e editor. |0 http://id.loc.gov/authorities/names/n99031484 |1 http://isni.org/isni/0000000037493620. | |
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