<i>Mycena</i> genomes resolve the evolution of fungal bioluminescence.
Saved in:
| Online Access: |
Full Text (via OSTI) |
|---|---|
| Corporate Author: | |
| Format: | eBook |
| Language: | English |
| Published: |
Washington, D.C. : Oak Ridge, Tenn. :
United States. Department of Energy. Office of Science ; Distributed by the Office of Scientific and Technical Information, U.S. Department of Energy,
2020.
|
| Abstract: | Mushroom-forming fungi in the order Agaricales represent an independent origin of bioluminescence in the tree of life; yet the diversity, evolutionary history, and timing of the origin of fungal luciferases remain elusive. We sequenced the genomes and transcriptomes of five bonnet mushroom species (<italic>Mycena</italic>spp.), a diverse lineage comprising the majority of bioluminescent fungi. Two species with haploid genome assemblies ̃150 Mb are among the largest in Agaricales, and we found that a variety of repeats between<italic>Mycena</italic>species were differentially mediated by DNA methylation. We show that bioluminescence evolved in the last common ancestor of mycenoid and the marasmioid clade of Agaricales and was maintained through at least 160 million years of evolution. Analyses of synteny across genomes of bioluminescent species resolved how the luciferase cluster was derived by duplication and translocation, frequently rearranged and lost in most<italic>Mycena</italic>species, but conserved in the<italic>Armillaria</italic>lineage. Luciferase cluster members were coexpressed across developmental stages, with the highest expression in fruiting body caps and stipes, suggesting fruiting-related adaptive functions. Our results contribute to understanding a de novo origin of bioluminescence and the corresponding gene cluster in a diverse group of enigmatic fungal species. |
|---|---|
| Item Description: | Published through Scitech Connect. 11/23/2020. "Journal ID: ISSN 0027-8424." Ke, Huei-Mien ; Lee, Hsin-Han ; Lin, Chan-Yi Ivy ; Liu, Yu-Ching ; Lu, Min R. ; Hsieh, Jo-Wei Allison ; Chang, Chiung-Chih ; Wu, Pei-Hsuan ; Lu, Meiyeh Jade ; Li, Jeng-Yi ; et al; |
| Physical Description: | Size: p. 31267-31277 : digital, PDF file. |