Opioids : pharmacology, abuse, and addiction / Silvia L. Cruz, editor.
Opioids are the mainstay in pain treatment and can be invaluable medications in palliative care. However, they are also responsible for the vast majority of preventable deaths related to drug use. This book presents an overview of the social and pharmacological aspects of opioid effects, aiming to p...
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| Online Access: |
Full Text (via Springer) |
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| Other Authors: | |
| Format: | eBook |
| Language: | English |
| Published: |
Cham :
Springer,
[2022]
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| Subjects: |
| Summary: | Opioids are the mainstay in pain treatment and can be invaluable medications in palliative care. However, they are also responsible for the vast majority of preventable deaths related to drug use. This book presents an overview of the social and pharmacological aspects of opioid effects, aiming to provide researchers and health professionals with a firm understanding of their effects and mechanisms of action. The first section reviews the history of opioids from ancient civilizations to the current opioid crisis, gives voice to opioid users through first-hand testimonies, analyzes the existing international drug treatment agreements, and presents structured interventions for persons who misuse opioids. The second section covers state-of-the-art advances in the medical use of opioids, opioid-induced signal transduction, opioids in pain management, opioid use disorders and their treatment. It also presents an updated view of opioids as regulators of inflammation and host defense against pathogens and damage. The overall aim of this book is to provide the reader with a deeper knowledge of this field despite the complexities associated with the existence of numerous ligands, receptor subtypes, and complex pharmacological profiles. To this end, the chapter authors are specialists in the field who also have extensive experience in teaching, hoping to lend their expertise in translating complex concepts into comprehensive and clear explanations. |
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| Item Description: | Includes index. |
| Physical Description: | 1 online resource (xv, 387 pages) : illustrations (chiefly color) |
| Bibliography: | References -- Chapter 2: The Two Sides of Opioid Use: Unmet Needs of Opioids for Pain Management and the Role of Opioids in Substance Use Disorders -- 2.1 Introduction -- 2.1.1 Background -- 2.2 Drug Markets -- 2.2.1 Unregulated Markets -- 2.2.2 Regulated Markets -- 2.3 Opioids for Pain Management -- 2.3.1 Pain Treatment Needs -- 2.3.2 Disparities in the Availability of Pain Medication -- 2.4 The Global Opioid Problem -- 2.4.1 Stigma, Discrimination, and Human Rights -- 2.4.2 Opioid Agonist Therapy (OAT) -- 2.5 Recommendations -- References -- Chapter 3: Opioid Markets and Special Populations. |
| ISBN: | 9783031099366 3031099362 |
| Source of Description, Etc. Note: | Source of description: Online resource; title from PDF title page (SpringerLink, viewed October 19, 2022) |