Neurodegenerative diseases / Donald B. Calne.

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Bibliographic Details
Other Authors: Calne, Donald B. (Donald Brian)
Format: Book
Language:English
Published: Philadelphia : W.B. Saunders Co., ©1994.
Subjects:
Table of Contents:
  • Basic sciences
  • Structures of neurons in the aging nervous system
  • Vulnerability of specific neurons to aging
  • Molecular biology of aging in the nervous system: a synopsis of the levels of mechanisms
  • Lewy bodies
  • Neurofibrillary tangles
  • Beta-protein fibrillogenesis and neuritic plaques
  • Neurotransmitters in neurodegeneration
  • Neurotransmitter receptors in neurodegeneration
  • Tissue culture models of neurodegeneration
  • Free radicals, oxidative stress and neurodegeneration
  • Glutamate excitotoxicity as a possible pathogenetic mechanism in chronic neurodegeneration
  • Growth factors and neurodegeneration
  • Mitochondrial disturbances in neurodegeneration
  • Susceptibility to neurotoxins
  • Organic neurotoxicants
  • Inorganic neurotoxins in dementia caused by neurodegeneration
  • Inorganic neurotoxins in neurodegenerative disorders without primary dementia
  • Neurodegeneration and the immune system. (cont) Infectious and noninfectious amyloidoses of the brain: systemic amyloidoses as predictive models in transmissible and nontransmissible amloidotic neurodegeneration of Creutzfeldt-Jakob disease and aging brain and Alzheimer's disease
  • Bacteria and neurodegeneration
  • Molecular genetic approaches to neurodegenerative disease
  • Compensatory mechanisms in central neurodegenerative disease
  • Animal models of neurodegenerative disease
  • Clinical sciences
  • Normal aging of the nervous system
  • Epidemiological overview of amyotrophic lateral sclerosis, Parkinson's disease and dementia of the Alzheimer type
  • Positron emission tomography
  • Magnetic resonance imaging in neurodegenerative diseases
  • Amyotrophic lateral sclerosis
  • Pathogenic mechanisms in amyotrophic lateral sclerosis and other motor neuron disorders
  • Clinical electrophysiology of amyotrophic lateral sclerosis
  • Natural history nd clinical features of amyotrophic lateral sclerosis and related motor neuron diseases
  • Treatment of amyotrophic lateral sclerosis. (cont) Parkinson's disease
  • Pathology of Parkinson's disease
  • Clinical features and natural history of Parkinson's disease (special consideration of aging)
  • Treatment of Parkinson's disease
  • Dementia of Alzheimer's type
  • Pathology of Alzheimer's disease
  • Cognitive changes in dementia of the Alzheimer type
  • Clinical features and natural history of Alzheimer's disease
  • Rational therapeutic strategies for Alzheimer's disease
  • Other eurodegenerative disorders
  • Wilson's disease (progressive hepatolenticular degeneration)
  • Huntington's disease
  • Idiopathic torsion dystonia
  • Essential tremor
  • Shy-drager syndrome (and multiple system atrophy)
  • Progressive supranuclear palsy
  • Cerebellar degenerations
  • Hallervorden-Spatz syndrome: an iron-storage disease
  • Sudanophilic (orthochromatic) leukodystrophies
  • Transmissible human spongiform encephalopathy (infectious cerebral myloidosis): Creutzfeldt-Jakob disease, Gerstmann-Straussler-Scheinker syndrome and Kuru
  • Cortical-basal ganglionic degeneration
  • Guam neurodegeneration
  • Rare neurodegenerative disorders.