GTPases in biology / contributors, K. Aktories [and others] ; editors, Burton F. Dickey and Lutz Birnbaumer.

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Bibliographic Details
Other Authors: Aktories, K., Dickey, Burton F., 1953-, Birnbaumer, Lutz
Format: Book
Language:English
Published: Berlin ; New York : Springer, ©1993.
Series:Handbook of experimental pharmacology ; v. 108.
Subjects:
Table of Contents:
  • pt. 2. Signal transduction by trimeric G proteins
  • Cellular architecture and its role in signal transduction
  • G-proteins have properties of multimeric proteins: an explanation for the role of GTPases in their dynamic behavior
  • G-protein coupled receptors
  • Superfamily: molecular modelling
  • Role of receptor kinases and arrestin-like proteins in G-protein-linked receptor desensitization
  • Trimeric G-proteins
  • Qualitative and quantitative characterization of the distribution of G-protein α subunits in mammals
  • Subunit interactions of heterotrimeric G-proteins
  • G-protein α subunit chimeras reveal specific regulatory domains encoded in the primary sequence
  • GTPase cycle: transducin
  • Transcriptional, posttranscriptional and posttranslational regulation of G-proteins and adrenergic receptors
  • G-protein subunit lipidation in membrane association and signaling
  • Phosphorylation of heterotrimeric G-protein
  • Receptor to effector signaling through G-proteins: βγ dimers join α subunits in the world of higher eukaryotes
  • Effectors of G-proteins.
  • (cont) Molecular diversity of mammalian adenylyl cyclases: functional consequences
  • Light-regulated cGMP phosphodiesterase of vertebrate photoreceptors: structure and mechanism of activation by Gta
  • High-voltage activated Ca²⁺ channel
  • Phospholipase C-β isozymes activated by Gaq members
  • Stimulation of phospholipase C by G-protein βγ subunits
  • Rhodopsin/G-protein interaction
  • Fast kinetics of G-protein function in vivo
  • Yeast pheromone response G-protein
  • Ga proteins in Drosophila: structure and developmental expression
  • Signal transduction by G-proteins in Dictyostelium discoideum
  • Functional expression of mammalian receptors and G-proteins in yeast
  • G-proteins in the signal transduction of the neutrophil
  • Hormonal regulation of phospholipid metabolism via G-proteins: phosphoinositide phospholipase C and phosphatidylcholine phospholipase D
  • Hormonal regulation of phospholipid metabolism via G-proteins II: PLA₂ and inhibitory regulation of PLC
  • G-protein regulation of phospholipase C in the turkey erythrocyte
  • Hormonal inhibition of adenylyl cyclase by αi and βγ, αi or βγ, αi and/or βγ
  • (cont) Neurobiology of G₀
  • Involvement of pertussis-toxin-sensitive G-proteins in the modulation of Ca²⁺ channels by hormones and neurotransmitters
  • Regulation of cell growth and proliferation by G₀
  • Role of nucleoside diphosphate kinase in G-protein action
  • G-protein regulation of cardiac K⁺ channels
  • Modulation of K⁺ channels by G-proteins
  • ATP-sensitive K⁺ channel: properties, occurrence, role in regulation of insulin secretion
  • Modulation of maxi-calcium-activated K channels: role of ligands, phosphorylation and G-proteins
  • Regulation of the endosomal proton translocating ATPase (H⁺-ATPase) and endosomal acidification by G-proteins
  • cAMP-independent regulation of adipocyte glucose transport activity and other metabolic processes by a complex of receptors and their associated G-proteins.