Molecular analysis of B lymphocyte development and activation / H. Singh and R. Grosschedl (ed.)
The B lymphocyte lineage represents an important paradigm for exploring the molecular mechanisms underlying cell fate specification, differentiation and cellular activation. In the past five years, major advances have been achieved in our understanding of the transcriptional control of early B cell...
Saved in:
| Online Access: |
Full Text (via Springer) |
|---|---|
| Other Authors: | , |
| Format: | eBook |
| Language: | English |
| Published: |
Berlin ; New York :
Springer,
©2005.
|
| Series: | Current topics in microbiology and immunology ;
290. |
| Subjects: |
| Summary: | The B lymphocyte lineage represents an important paradigm for exploring the molecular mechanisms underlying cell fate specification, differentiation and cellular activation. In the past five years, major advances have been achieved in our understanding of the transcriptional control of early B cell development and terminal plasma cell differentiation. In addition new insights became available for the processes of B cell activation, class switch recombination and somatic hypermutation. Many of the new findings and their implications for a molecular understanding of B cell biology in particular and cell differentiation in general are covered in this volume. |
|---|---|
| Physical Description: | 1 online resource (viii, 255 pages) : illustrations. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 3540230904 9783540230908 9783540263630 3540263632 |
| ISSN: | 0070-217X ; |