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Particle deposition in human and canine tracheobronchial casts [electronic resource]

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Bibliographic Details
Online Access:	Online Access
Corporate Author:	United States. Department of Energy. Chicago Operations Office (Researcher)
Format:	Government Document Electronic eBook
Language:	English
Published:	Washington, D.C : Oak Ridge, Tenn. : United States. Dept. of Energy. Assistant Secretary for Environmental Protection, Safety, and Emergency Preparedness ; distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, 1991.
Subjects:	Rare Gases. Excretion. Daughter Products. Beta Decay Radioisotopes. Heavy Nuclei. Compartments. Document Types. Mathematical Models. Mammals. Beta-minus Decay Radioisotopes. Intake. Even-even Nuclei. Dogs. Aerosols. Isotopes. Radioactive Aerosols. Fluids. Animals. Elements. Dispersions. Exhalation. Retention. Gases. Colloids. Polonium Isotopes. Nonmetals. Progress Report. Respiratory System. Minutes Living Radioisotopes. Respiration. Flow Rate. Polonium 218. Inhalation. Vertebrates. Particle Size. Flow Models. Clearance. Sols. Alpha Decay Radioisotopes. Size. Nuclei. Radon. Radioisotopes. Radiation, Thermal, And Other Environ. Pollutant Effects On Living Orgs. And Biol. Mat..

Description
Abstract:	The aim of this work is to measure deposition patterns and efficiencies of aerosol particles within realistic, single-pathway physical models of the tracheobronchial airways of humans and experimental animals over a range of particle sizes for a variety of respiratory modes and rates. This will provide data needed to assess the dose to the bronchial epithelium from inhaled radon progeny. In the current year theoretical studies based on a developing flow model were extended. We concluded that although the developing flow model is better predictor of the data than assumption of parabolic flow, the predicated deposition is significantly lower than that predicted by our best fit equation. The mass size dispersion of particles classified according to their electrical mobilities was also studies. For the conditions tested, doubly charged particles constituted 9--13% of the total particle number concentration and 24--48% of the total mass concentration. We demonstrated that the multiply charged particles are effectively removed, and nearly monodisperse particles produced, if an impactor is placed in the aerosol generation system. A condensation aerosol generator was constructed and tested for the production of high concentrations of radioactively tagged aerosol particles with diameters from 0.2 to 10μm. 9 refs.
Item Description:	Published through the Information Bridge: DOE Scientific and Technical Information. 01/15/1991. "doe/er/60592-6" "DE91007364" Cohen, B.S. New York Univ., NY (USA). Medical Center.
Physical Description:	Pages: (64 p) : digital, PDF file.