RNA technologies and their applications [electronic resource] / volume editors, Volker A. Erdmann, Jan Barciszewski.
RNA technologies are the driving forces of modern medicine and biotechnology. They combine the fields of biochemistry, chemistry, molecular biology, cell biology, physics, nanotechnology and bioinformatics. The combination of these topics is set to revolutionize the medicine of tomorrow. After more...
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| Online Access: |
Full Text (via Springer) |
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| Other Authors: | , |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Berlin ; London :
Springer,
2010.
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| Series: | RNA technologies.
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| Subjects: |
MARC
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| 245 | 0 | 0 | |a RNA technologies and their applications |h [electronic resource] / |c volume editors, Volker A. Erdmann, Jan Barciszewski. |
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| 490 | 1 | |a RNA Technologies. | |
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a The key features of RNA silencing / Kuniaki Saito [and others] -- Selected strategies for the delivery of siRNA in vitro and in vivo / Sandra D. Laufer [and others] -- RNAi suppression and its application / Xiaoping Yi, Rui Lu -- Strategies to prevent siRNA-triggered cellular toxicity / Matthias Bauer -- RNAi in malignant brain tumors: relevance to molecular and translational research / Mitsutoshi Nakada [and others] -- Silencing Huntington's disease gene with RNAi / Yu Zhang, Robert M. Friedlander -- Application of Dicer-substrate siRNA in pain research / Philippe Sarret [and others] -- RNAi treatment of HIV-1 infection / Karin J. von Eije, Ben Berkhout -- Application of RNA interference to treat conditions associated with dysregulation of transient receptor potential vanilloid 1 channel / Vickram Ramkumar [and others] -- Harnessing RNAi-based functional genomics to unravel the molecular complexity underlying skin pigment variation / Hsiang Ho [and others] | |
| 505 | 0 | |a MRNA structure and its effects on posttranscriptional gene silencing / Stephen I. Rudnick, Veenu Aishwarya, Alan M. Gewirtz -- Antisense RNA-mediated regulation of the p53 tumor suppressor / Marianne Farnebo, Klas G. Wiman -- Antisense oligonucleotides: insights from preclinical studies and clinical trials / Doreen Kunze, Kai Kraemer, Susanne Fuessel -- What can the new hammerhead ribozyme structures teach us about design? / William G. Scott -- microRNA biogenesis and its impact on RNA interference / Stefanie Grund, Sven Diederichs -- MicroRNAs in epithelial antimicrobial immunity / Jun Liu [and others] -- Emerging roles of long noncoding RNAs in gene expression and intracellular organization / Tetsuro Hirose -- Noncoding RNAs as therapeutic targets / Maciej Szymański, Jan Barciszewski -- Noncoding RNAs at H19/IGF2 locus: role in imprinting, gene expression, and associated pathologies / Nahalie Berteaux, Nathalie Spruyt, Eric Adriaenssens. | |
| 520 | |a RNA technologies are the driving forces of modern medicine and biotechnology. They combine the fields of biochemistry, chemistry, molecular biology, cell biology, physics, nanotechnology and bioinformatics. The combination of these topics is set to revolutionize the medicine of tomorrow. After more than 15 years of extensive research in the field of RNA technologies, the first therapeutics are ready to reach the first patients. Thus we are witnessing the birth of a very exciting time in the development of molecular medicine, which will be based on the methods of RNA technologies. This volume is the first of a series. It covers various aspects of RNA interference and microRNAs, although antisense RNA applications, hammerhead ribozyme structure and function as well as non-coding RNAs are also discussed. The authors are internationally highly respected experts in the field of RNA technologies. | ||
| 650 | 0 | |a Antisense RNA. |0 http://id.loc.gov/authorities/subjects/sh89003559. | |
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| 650 | 7 | |a Catalytic RNA. |2 fast |0 (OCoLC)fst00848887. | |
| 700 | 1 | |a Erdmann, V. A. |q (Volker A.), |d 1941-2015. |0 http://id.loc.gov/authorities/names/n85348325 |1 http://isni.org/isni/0000000116901952. | |
| 700 | 1 | |a Barciszewski, Jan. |0 http://id.loc.gov/authorities/names/n85811217 |1 http://isni.org/isni/0000000081568570. | |
| 776 | 0 | 8 | |i Print version: |t RNA technologies and their applications. |d Berlin ; London : Springer, 2010 |z 9783642121678 |w (OCoLC)551431152. |
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