Neurogenesis in the adult brain II [electronic resource] : clinical implications / Tatsunori Seki [and others], editors.
The discovery of adult neurogenesis caused a paradigm shift in the neurosciences. For more than 100 years, it was believed that adult neurons do not regenerate. Joseph Altman and Fernando Nottebohm found proof to the contrary and changed the course of history. Their research, included here, provides...
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| Language: | English |
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Tokyo ; New York :
Springer,
©2011.
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Table of Contents:
- Neurogenesis in the Adult Brain II; Preface; Contents; Contents of Volume I; Contributors; Chapter 1: Neurogenesis in Monkey and Human Adult Brain; 1.1 Introduction; 1.2 Materials and Methods; 1.3 Results; 1.4 Discussion; References; Chapter 2: Adult Neurogenesis in Parkinson's Disease; 2.1 Introduction; 2.2 Adult Neurogenesis of SN in PD and PD Models; 2.3 Adult Neurogenesis of SVZ in PD and PD Models; 2.4 Adult Neurogenesis of OB in PD and PD Models; 2.5 Adult Neurogenesis in Genetic PD Models; 2.6 Therapeutic Window for Adult Neurogenesis in PD; 2.7 Conclusion; References.
- Chapter 3: Adult Neurogenesis in Epilepsy3.1 Introduction; 3.2 Summary; References; Chapter 4: Stress Disorders; 4.1 The Concept of Stress; 4.2 Stress and Neurogenesis; 4.3 Stress Disorders and Neurogenesis; 4.4 Conclusion; References; Chapter 5: Depression; 5.1 Depression; 5.2 Stress Decreases Neurogenesis; 5.3 Is Decreased Neurogenesis One Pathology of Depression?; 5.4 The Involvement of Neurogenesis in the Therapeutic Effects of Antidepressant Treatment; 5.5 Concluding Remarks; References; Chapter 6: Impaired Neurogenesis as a Risk Factor for Schizophrenia and Related Mental Diseases.
- 6.1 Introduction6.2 Risk Factors for Schizophrenia; 6.3 Biomarkers/Endophenotypes for Schizophrenia; 6.4 Neurogenesis and Prepulse Inhibition; 6.5 The "Neurogenesis Theory" for Schizophreniaand Other Mental Disorders; 6.6 Several Methods for Increasing Neurogenesis; 6.7 Increasing Neurogenesis with PUFAs; 6.8 Concluding Remarks; References; Chapter 7: Neurogenesis from Endogenous Neural Stem Cells After Stroke: A Future Therapeutic Target to Promote Functional Restoration?; 7.1 Introduction; 7.2 Stroke-Induced Neurogenesis in Rodents; 7.3 Stroke-Induced Neurogenesis in Humans.
- 7.4 Functional Consequences of Stroke-Induced Neurogenesis7.5 Neurogenesis as a Potential Therapeutic Target After Stroke; 7.6 Clinical Perspectives; References; Chapter 8: Perspectives of "PUFA-GPR40 Signaling" Crucial for Adult Hippocampal Neurogenesis; 8.1 Background; 8.2 PUFA; 8.3 FABP; 8.4 GPR40; 8.5 CREB; 8.6 BDNF; 8.7 Conclusion; References; Chapter 9: Adult Neurogenesis and Neuronal Subtype Specification in the Neocortex*; 9.1 Introduction; 9.2 Adult Neurogenesis: Historical Perspective; 9.3 Controversy on Adult Neurogenesis in the Neocortex.
- 9.4 Induction of Neurogenesis in the Adult Neocortex9.5 Molecular Controls over Development of Neuronal Subtypes; 9.6 Conclusions; References; Chapter 10: Culturing Adult Neural Stem Cells: Application to the Study of Neurodegenerative and Neuropsychiatric Pathology; 10.1 Introduction; 10.2 Procedures of the Neurosphere Assay; 10.3 Application of the Neurosphere Assay to Understanding In Vivo Neural Stem Cell Function; 10.4 Concluding Remarks; References; Index.