Next generation sequencing in cancer research. Volume 1, Decoding the cancer genome / Wei Wu, Hani Choudhry, Editors.
Next Generation Sequencing (NGS) technology has placed important milestones in the life science and changed the direction in biomedical science inclucing cancer. Scientists around the world are attempting to find the root cause of cancer and they are looking for more direct and effective means to cu...
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| Other title: | Decoding the cancer genome. |
| Format: | eBook |
| Language: | English |
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New York, NY :
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©2013.
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| 245 | 0 | 0 | |a Next generation sequencing in cancer research. |n Volume 1, |p Decoding the cancer genome / |c Wei Wu, Hani Choudhry, Editors. |
| 246 | 3 | 0 | |a Decoding the cancer genome. |
| 264 | 1 | |a New York, NY : |b Springer, |c ©2013. | |
| 300 | |a 1 online resource (xxiii, 383 pages) : |b illustrations. | ||
| 336 | |a text |b txt |2 rdacontent. | ||
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| 504 | |a Includes bibliographical references at chapter ends, and index. | ||
| 505 | 0 | 0 | |t The evolution of high-throughput sequencing technologies : from Sanger to single-molecule sequencing / |r Chee-Seng Ku, |r Yudi Pawitan, |r Mengchu Wu, |r Dimitrios H. Roukos, and |r David N. Cooper -- |t Next-generation sequencing in cancer epigenomics and potential clinical applications / |r Hong Kiat Ng, |r Dimitrios H. Roukos, |r Barry Iacopetta, and |r Chee-Seng Ku -- |t Next-generation sequencing for cancer genomics / |r Aarti N. Desai and |r Abhay Jere -- |t Genomic landscape of cancer metastasis / |r Arvind K. Singla, |r Chandini Thirukkumaran, |r Rajiv Dixit, and |r Wei Wu -- |t Mapping the HIF transcription factor in cancer by ChIP-seq technology / |r Johannes Schödel and |r David R. Mole -- |t Application of next-generation sequencing to analysis of TGFß/SMAD4 targets in ovarian cancer / |r Russell Bonneville, |r Kenneth Nephew, and |r Victor X. Jin -- |t Targeted sequencing strategies in cancer research / |r HoJoon Lee, |r Billy T. Lau, and |r Hanlee P. Ji -- |t Comprehensive genomic alterations in common cancer cell lines revealed by exome sequencing / |r Han Chang, |r Donald G. Jackson, |r Paul S. Kayne, |r Petra B. Ross-Macdonald, |r Rolf-Peter Ryseck, and |r Nathan O. Siemers -- |t Application of next-generation sequencing in RNA biomarker discovery in cancer research / |r Stephen P. Fink and |r Kishore Guda -- |
| 505 | 0 | 0 | |t Understanding the role of long noncoding RNAs in the cancer genome / |r Wei Wu and |r Jennifer A. Chan -- |t Identification of piRNAs in HeLa cells by massive parallel sequencing / |r Yilu Lu and |r Yongxin Ma -- |t MicroRNA expression in breast cancer revealed by deep sequencing technology / |r Thalia A. Farazi, |r Carl S. Leonhardt, and |r Thomas Tuschl -- |t RNA-Seq in prostate cancer research / |r ShanCheng Ren, |r Min Qu, and |r Yinghao Sun -- |t Next-generation sequencing for high-throughput RNA interference screens / |r Toby M. Ward, |r Anna-Maria Jegg, and |r Elizabeth Iorns -- |t Assessment of mapping and SNP-detection algorithms for next-generation sequencing data in cancer genomics / |r Weixin Wang, |r Feng Xu, and |r Junwen Wang -- |t Applications of very low-coverage sequencing in cancer genomics : copy number, virus detection and survival / |r Henry M. Wood -- |t Tumor phylogenetics in the NGS era : strategies, challenges, and future prospects / |r Ayshwarya Subramanian, |r Stanley Shackney, and |r Russell Schwartz -- |t Impact and challenges in assessing tumor purity by next-generation sequencing / |r Xiaoping Su, |r Gabriel G. Malouf, and |r Francisco J. Esteva. |
| 520 | |a Next Generation Sequencing (NGS) technology has placed important milestones in the life science and changed the direction in biomedical science inclucing cancer. Scientists around the world are attempting to find the root cause of cancer and they are looking for more direct and effective means to cure cancer. This journey to conquer cancer is more optimistic now with the unfolding of the cancer genome. This book focuses on the application of various NGS in the frontier cancer genome research. The 18 chapters in this volume have been written by scientists with many outstanding contributions in their area and the join effort has created comprehensive insightful view on (1) Overview of next generation sequencing technology in cancer genome research (2) Genome regulation and targeted sequencing in cancer (3) RNA transcriptome (coding and non-coding) in cancer genome (4)The challenges of computational biology for cancer genome study. This book is a state-of-the-art reference to all scientific researchers and onologists who are interested in the understanding of the cancer initiatome at whole genome scale and to those are keen to translate the 'base pairs to bedside' for better management of cancer patients in the era of personalized medicine. | ||
| 546 | |a English. | ||
| 588 | 0 | |a Online resource; title from PDF title page (SpringerLink, viewed August 20, 2013) | |
| 650 | 0 | |a Cancer genes. |0 http://id.loc.gov/authorities/subjects/sh2006006635. | |
| 650 | 0 | |a Cancer |x Genetic aspects. |0 http://id.loc.gov/authorities/subjects/sh85019509. | |
| 650 | 0 | |a Nucleotide sequence. |0 http://id.loc.gov/authorities/subjects/sh85093159. | |
| 650 | 7 | |a Cancer genes. |2 fast |0 (OCoLC)fst01765208. | |
| 650 | 7 | |a Cancer |x Genetic aspects. |2 fast |0 (OCoLC)fst00845368. | |
| 650 | 7 | |a Nucleotide sequence. |2 fast |0 (OCoLC)fst01041106. | |
| 700 | 1 | |a Wu, Wei, |c Dr., |e editor. |0 http://id.loc.gov/authorities/names/nb2010031320 |1 http://isni.org/isni/0000000107490485. | |
| 700 | 1 | |a Choudhry, Hani, |e editor. |0 http://id.loc.gov/authorities/names/n2014181856. | |
| 776 | 0 | 8 | |i Printed edition: |z 9781461476443. |
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