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|a (TOE)ost5663415
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|a (TOE)5663415
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|a TOE
|c TOE
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|a GDWR
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|a 63
|2 edbsc
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|a E 1.99:doe/ev/03110-31
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|a E 1.99:doe/ev/03110-31
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|a doe/ev/03110-31
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|a Cellular heredity in haploid cultures of somatic cells. Progress report, August 1978-September 1979. [ICR 2A celline (frogs)]
|h [electronic resource]
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| 260 |
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|a Washington, D.C :
|b United States. Department of Energy ;
|a Oak Ridge, Tenn. :
|b distributed by the Office of Scientific and Technical Information, U.S. Department of Energy,
|c 1979.
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| 300 |
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|a Pages: 12 :
|b digital, PDF file.
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| 336 |
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|a text
|b txt
|2 rdacontent.
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| 337 |
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|a computer
|b c
|2 rdamedia.
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| 338 |
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|a online resource
|b cr
|2 rdacarrier.
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| 500 |
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|a Published through SciTech Connect.
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| 500 |
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|a 10/01/1979.
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| 500 |
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|a "doe/ev/03110-31"
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| 500 |
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|a Freed, J J.
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3 |
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|a During the past year, studies were continued on the relation of ultraviolet mutagenesis to DNA repair in cultures of the haploid frog cell line ICR 2A. The method of irradiation of cells in suspension was improved by construction of an improved detector with major sensitivity to the 254 nm Hg resonance line, to give better estimates of actual exposure of the cells. Using this method, dose-response and dose-fractionation studies on irradiation of ouabain resistance were carried out. The uv induction of this phenotype in the ICR 2A cell line was found to be less than that necessary for adequate analysis of dose-response curves. Cell fusion experiments using frog and mouse cells revealed an enhancement of mutagenesis in the mouse parent that will be explored in further work.
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| 536 |
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|b AC02-76EV03110.
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| 650 |
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7 |
|a Information.
|2 local.
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| 650 |
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|a Recovery.
|2 local.
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| 650 |
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|a Experimental Data.
|2 local.
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| 650 |
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7 |
|a Genetic Effects.
|2 local.
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| 650 |
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7 |
|a Biological Repair.
|2 local.
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| 650 |
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7 |
|a Organic Compounds.
|2 local.
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| 650 |
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7 |
|a Mutagenesis.
|2 local.
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| 650 |
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7 |
|a Haploidy.
|2 local.
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| 650 |
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7 |
|a Biological Radiation Effects.
|2 local.
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| 650 |
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7 |
|a Electromagnetic Radiation.
|2 local.
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| 650 |
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7 |
|a Radiation Effects.
|2 local.
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| 650 |
|
7 |
|a Biological Recovery.
|2 local.
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| 650 |
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7 |
|a Dose-response Relationships.
|2 local.
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| 650 |
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|a Correlations.
|2 local.
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| 650 |
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|a Mutations.
|2 local.
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| 650 |
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|a Data Forms.
|2 local.
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| 650 |
|
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|a Biological Effects.
|2 local.
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| 650 |
|
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|a Ultraviolet Radiation.
|2 local.
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| 650 |
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|a Repair.
|2 local.
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| 650 |
|
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|a Numerical Data.
|2 local.
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| 650 |
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|a Fractionated Irradiation.
|2 local.
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| 650 |
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|a Irradiation.
|2 local.
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| 650 |
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|a Animal Cells.
|2 local.
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| 650 |
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|a Ploidy.
|2 local.
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| 650 |
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7 |
|a Nucleic Acids.
|2 local.
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| 650 |
|
7 |
|a Cell Cultures.
|2 local.
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| 650 |
|
7 |
|a Isolated Values.
|2 local.
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| 650 |
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7 |
|a Radiations.
|2 local.
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| 650 |
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7 |
|a Dna.
|2 local.
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| 650 |
|
7 |
|a Genetic Radiation Effects.
|2 local.
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| 650 |
|
7 |
|a Radioinduction.
|2 local.
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| 650 |
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7 |
|a Data.
|2 local.
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| 650 |
|
7 |
|a Radiation, Thermal, And Other Environ. Pollutant Effects On Living Orgs. And Biol. Mat..
|2 edbsc.
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| 710 |
2 |
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|a Alabama A & M University.
|4 res.
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| 710 |
1 |
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|a United States.
|b Department of Energy.
|4 spn.
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| 710 |
1 |
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|a United States.
|b Department of Energy.
|b Chicago Operations Office.
|4 res.
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| 710 |
1 |
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|a United States.
|b Department of Energy.
|b Office of Scientific and Technical Information.
|4 dst.
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| 856 |
4 |
0 |
|u http://www.osti.gov/servlets/purl/5663415/
|z Online Access
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| 907 |
|
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|a .b77103889
|b 03-07-23
|c 04-22-14
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| 998 |
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|a web
|b 04-22-14
|c f
|d m
|e p
|f eng
|g dcu
|h 0
|i 1
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| 956 |
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|a Information bridge
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|s 640dee82-51be-575a-836e-c0e3d68e1589
|
| 952 |
f |
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|p Can circulate
|a University of Colorado Boulder
|b Online
|c Online
|d Online
|e E 1.99:doe/ev/03110-31
|h Superintendent of Documents classification
|i web
|n 1
|
