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|a 10.1007/978-94-017-8914-1
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|a RC372
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|a A view from the bench /
|c Helen E. Scharfman, Paul S. Buckmaster, editors.
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| 264 |
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1 |
|a Dordrecht :
|b Springer,
|c 2014.
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| 300 |
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|a 1 online resource :
|b illustrations.
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|a Advances in experimental medicine and biology ;
|v volume 813.
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| 500 |
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|a Festschrift for Philip A. Schwartzkroin.
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| 504 |
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|a Includes bibliographical references and index.
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| 505 |
0 |
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|a How Can We Identify Ictal and Interictal Abnormal Activity? -- What Is the Clinical Relevance of In Vitro Epileptiform Activity? -- What Is the Importance of Abnormal "Background" Activity in Seizure Generation? -- What Is a Seizure Focus? -- What Is a Seizure Network? Long-Range Network Consequences of Focal Seizures -- What Is a Seizure Network? Very Fast Oscillations at the Interface Between Normal and Epileptic Brain -- Is There Such a Thing as "Generalized" Epilepsy? -- Are There Really "Epileptogenic" Mechanisms or Only Corruptions of "Normal" Plasticity? -- When and How Do Seizures Kill Neurons, and Is Cell Death Relevant to Epileptogenesis? -- How Is Homeostatic Plasticity Important in Epilepsy? -- Is Plasticity of GABAergic Mechanisms Relevant to Epileptogenesis? -- Do Structural Changes in GABA Neurons Give Rise to the Epileptic State? -- Does Mossy Fiber Sprouting Give Rise to the Epileptic State? -- Does Brain Inflammation Mediate Pathological Outcomes in Epilepsy? -- Are Changes in Synaptic Function That Underlie Hyperexcitability Responsible for Seizure Activity? -- Does Epilepsy Cause a Reversion to Immature Function? -- Are Alterations in Transmitter Receptor and Ion Channel Expression Responsible for Epilepsies? -- How Do We Make Models That Are Useful in Understanding Partial Epilepsies? -- Aligning Animal Models with Clinical Epilepsy: Where to Begin? -- What Non-neuronal Mechanisms Should Be Studied to Understand Epileptic Seizures? -- What Epilepsy Comorbidities Are Important to Model in the Laboratory? Clinical Perspectives -- Epilepsy Comorbidities: How Can Animal Models Help? -- What New Modeling Approaches Will Help Us Identify Promising Drug Treatments? -- What Are the Arguments For and Against Rational Therapy for Epilepsy? -- How Can Advances in Epilepsy Genetics Lead to Better Treatments and Cures? -- How Might Novel Technologies Such as Optogenetics Lead to Better Treatments in Epilepsy?
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|a Epilepsy
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|a Epilepsy
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|a Scharfman, Helen E.,
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|a Buckmaster, Paul S.,
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|0 http://id.loc.gov/authorities/names/nb2014021011.
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|a Schwartzkroin, P. A.
|q (Philip A.),
|e honouree.
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|z 9789401789134
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|0 http://id.loc.gov/authorities/names/n42001229.
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| 856 |
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|u https://colorado.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-94-017-8914-1
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