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Mechanisms of lymphocyte activation and immune regulation VI [electronic resource] : cell cycle and programmed cell death in the immune system / edited by Sudhir Gupta and J. John Cohen.

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Bibliographic Details
Online Access: Full Text (via Springer)
Corporate Author: International Conference on Lymphocyte Activation and Immune Regulation
Other Authors: Gupta, Sudhir, Cohen, J. John
Other title:Cell cycle and programmed cell death in the immune system.
Format: Electronic Conference Proceeding eBook
Language:English
Published: New York : Plenum Press, ©1996.
Series:Advances in experimental medicine and biology ; v. 406.
Subjects:
Lymphocytes > Congresses.
Cell cycle > Congresses.
Apoptosis > Congresses.
Apoptosis.
Cell cycle.
Lymphocytes.
Conference papers and proceedings.
Table of Contents:
  • I. Cell cycle and signaling pathways in apoptosis
  • Apoptosis/programmed cell death: a historical perspective
  • Apoptosis and its regulation
  • Mechansisms for recognition and phagocytosis of apoptotic lymphocytes by macrophages
  • Cytotoxic lymphocyte killing enters the ICE age
  • Cross-talk between ceramide and PKC activity in the control of apoptosis in WEHI-231
  • Cell cycle control of T cell apoptosis induced by activation through the T cell antigen receptor
  • Role of antibody signaling in inducing tumor dormancy
  • II. Apoptosis-regulating genes
  • Regulation of lymphoid apoptosis by Bcl-2 and Bcl-xl
  • The Epstein-Barr virus gene BHRF1, a homologue of the cellular oncogene Bcl-2, inhibits apoptosis induced by gamma radiation and chemotherapeutic drugs
  • Structure-function analysis of Bcl-2 family proteins: regulators of programmed cell death
  • Role of ICE-proteases in apoptosis
  • Fas-mediated apoptosis
  • Fas splicing variants and their effect on apoptosis
  • The role of FasL and TNF in the homeostatic regulation of immune responses
  • III. Apoptosis in B cells
  • Signals for survival and apoptosis in normal and neoplastic B lymphocytes
  • Regulation of B cell apoptosis
  • Apoptotic cell dealth in the chicken bursa of fabricius
  • Generation and regulation of B cell autoreactivity arising in the periphery
  • Inducible resistance to Fas-mediated apoptosis in primary B lymphocytes
  • IV. Apoptosis in T cells
  • The thymus and T cell death
  • Genetic regulation of apoptosis in the mouse thymus
  • Regulation of T cell activation by CD28 and CTLA4
  • Granzyme B-induced apoptosis
  • Mature T lymphocyte apoptosis in the healthy and diseased immune system
  • Autoimmunity due to defective NUR77, Fas, and TNF-RI apoptosis
  • Index.

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