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Contemporary Topics in Immunobiology : Self/Non-self Discrimination / edited by John J. Marchalonis, Nicholas Cohen.

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Bibliographic Details
Online Access: Full Text (via Springer)
Main Author: Marchalonis, John J.
Other Authors: Cohen, Nicholas
Format: eBook
Language:English
Published: Boston, MA : Springer US : Imprint : Springer, 1980.
Series:Contemporary topics in immunobiology ; 9.
Subjects:
Medicine.
Immunology.
Table of Contents:
  • 1 Discrimination of Self and Non-self in Plants
  • I. Introduction
  • II. Biology of Recognition Systems in Vascular Plants
  • III. Immunobiology of Recognition Systems
  • IV. Conclusions
  • V. References
  • 2 Discrimination of Self and Non-self in Invertebrates
  • I. Introduction
  • II. Non-self Recognition
  • III. Serum Factors
  • IV. Graft Studies and Invertebrate Histocompatibility Antigens
  • V. References
  • 3 Phylogeny of the Emergence of T-B Collaboration in Humoral Immunity
  • I. Introduction: Primary and Secondary Lymphoid Sites
  • II. Evidence of Lymphoid Heterogeneity: Differential Mitogenesis
  • III. Evidence of Lymphoid Heterogeneity from Thymic Ablation
  • IV. Evidence of Cell-Cell Collaboration in Ectotherms
  • V. Conclusion: Some Speculations with Respect to the Evolution of Immunity
  • VI. References
  • 4 Lymphoid-Cell Cooperation in Immune Responses of the Chicken
  • 5 Salamanders and the Evolution of the Major Histocompatibility Complex
  • I. Introduction
  • II. Does the MHC Exist in any Ectothermic Vertebrate?
  • III. Do Salamanders Have the MHC?
  • IV. Concluding Comments
  • V. References
  • 6 Membrane Immunoglobulins of Vertebrate Lymphocytes
  • I. Introduction
  • II. A Note on Methods for the Demonstration of Membrane Immunoglobulins
  • III. Surface Immunoglobulins of Vertebrate Lymphocytes
  • IV. Function of Lymphocyte-Surface Immunoglobulins
  • V. Concluding Comments
  • VI. References
  • 7 Idiotypes, T-Cell Receptors, and T-B Cooperation
  • I. Introduction
  • II. Immunoglobulin Genes
  • III. The Major Histocompatibility Complex
  • IV. Antigen Recognition by T Cells
  • V. Subpopulations of T Cells
  • VI. The High Frequency of Alloreactive T Cells and Their Responsiveness to Nominal Antigen
  • VII. T-Cell Receptors for Antigen Are Encoded in Conventional VH Genes
  • VIII. Self/Non-self Discrimination by T Cells
  • IX. The Association of Nominal Antigens with MHC Structures
  • X. Cellular Interactions in Antibody Responses
  • XI. Discussion
  • XII. Summary
  • XIII. References
  • 8 An Immunologic Network
  • I. Introduction
  • II. The Immune System and Connectivity through Antigen
  • III. Connectivity through Antigen and A Cells
  • IV. Complementary Idiotypes
  • V.A Minimal Network
  • VI. Regulation
  • VII. Is the Network Too Complex?
  • VIII. The Network and Disease
  • IX. Summary
  • X. References
  • 9 The Biological Function of the Major Histocompatibility Complex: Hypotheses
  • I. Introduction
  • II. Allograft Reaction
  • III. Genetic Control of Immune Responses
  • IV. Genetic Control of Complement Levels
  • V. MHC Associations with Susceptibility and Resistance to Disease
  • VI. Genetic Control of Traits Not Currently Classified as Immunological
  • VII. Further Analyses of the Importance of MHC Antigens and Genes
  • VIII. Conclusion
  • IX. References
  • 10 Molecular Interactions and Recognition Specificity of Surface Receptors
  • I. Introduction
  • II. Ground Rules
  • III. Cell-Surface Molecules Implicated as Receptors
  • IV. Structural Relationships among Surface Receptors
  • V. Binding Parameters of Receptors
  • VI. Combining Sites of Lectins and Antibodies
  • VII. Primary Binding and Subsequent Early Membrane Events
  • VIII. Conclusions: Primary Binding and Activation
  • IX. References.

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