Cancer cell signaling [electronic resource] : methods and protocols / edited by David M. Terrian.
The rapidly evolving nature of cell signaling research in cancer has necessitated a continuous updating of the methods used in its study, most recently to take into account the analysis of multiple members within a gene family. Cancer Cell Signaling: Methods and Protocols brings together all the maj...
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Online Access: |
Online Access |
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Other Authors: | |
Format: | Electronic eBook |
Language: | English |
Published: |
Totowa, N.J. :
Humana Press,
©2003.
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Series: | Methods in molecular biology (Clifton, N.J.) ;
v. 218. |
Subjects: |
Summary: | The rapidly evolving nature of cell signaling research in cancer has necessitated a continuous updating of the methods used in its study, most recently to take into account the analysis of multiple members within a gene family. Cancer Cell Signaling: Methods and Protocols brings together all the major methods of cell research that are scientifically grounded within the cancer biology field. Presented in step-by-step detail to ensure successful results, the methods include proven techniques for the investigation of apoptosis and cell death, complementary protocols for manipulating and/or monitoring oncogenic signals in cancer cells, and techniques for studying protein-protein interactions. Finally, there is a detailed protocol for capturing pure samples of malignant cells from frozen tissue specimens and two alternative techniques for analyzing their genomic DNA. Each method is described by a hands-on master of the technique and includes invaluable notes on troubleshooting and pitfalls to avoid. Cutting-edge and highly practical, Cancer Cell Signaling: Methods and Protocols provides today's cancer researchers with new, but well-proven, strategies and procedures for investigating how the signaling cascades essential to normal cell life are corrupted, as well as for developing new molecular tools for cancer therapy. |
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Physical Description: | 1 online resource (xiii, 333 pages) : illustrations. |
Bibliography: | Includes bibliographical references and index. |
ISBN: | 1588290751 9781588290755 1592593569 9781592593569 |
DOI: | 10.1385/1592593569 |
Source of Description, Etc. Note: | Print version record. |