Cancer cell signaling [electronic resource] : methods and protocols / edited by David M. Terrian.

The rapidly evolving nature of cell signaling research in cancer has necessitated a continuous updating of the methods used in its study, most recently to take into account the analysis of multiple members within a gene family. Cancer Cell Signaling: Methods and Protocols brings together all the maj...

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Bibliographic Details
Online Access: Online Access
Other Authors: Terrian, David M.
Format: Electronic eBook
Language:English
Published: Totowa, N.J. : Humana Press, ©2003.
Series:Methods in molecular biology (Clifton, N.J.) ; v. 218.
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Summary:The rapidly evolving nature of cell signaling research in cancer has necessitated a continuous updating of the methods used in its study, most recently to take into account the analysis of multiple members within a gene family. Cancer Cell Signaling: Methods and Protocols brings together all the major methods of cell research that are scientifically grounded within the cancer biology field. Presented in step-by-step detail to ensure successful results, the methods include proven techniques for the investigation of apoptosis and cell death, complementary protocols for manipulating and/or monitoring oncogenic signals in cancer cells, and techniques for studying protein-protein interactions. Finally, there is a detailed protocol for capturing pure samples of malignant cells from frozen tissue specimens and two alternative techniques for analyzing their genomic DNA. Each method is described by a hands-on master of the technique and includes invaluable notes on troubleshooting and pitfalls to avoid. Cutting-edge and highly practical, Cancer Cell Signaling: Methods and Protocols provides today's cancer researchers with new, but well-proven, strategies and procedures for investigating how the signaling cascades essential to normal cell life are corrupted, as well as for developing new molecular tools for cancer therapy.
Physical Description:1 online resource (xiii, 333 pages) : illustrations.
Bibliography:Includes bibliographical references and index.
ISBN:1588290751
9781588290755
1592593569
9781592593569
DOI:10.1385/1592593569
Source of Description, Etc. Note:Print version record.