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Apoptosis and cancer [electronic resource] : methods and protocols / edited by Gil Mor and Ayesha B. Alvero.

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Our understanding of the apoptotic pathway and its regulation has improved significantly in the last 10 years. However, as our knowledge of the intricate intracellular events increase, we realize the complexity of the regulatory mechanisms that control it. As such, Apoptosis and Cancer describes the...

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Bibliographic Details
Online Access: Online Access
Other Authors: Mor, Gil, Alvero, Ayesha B.
Format: Electronic eBook
Language:English
Published: Totowa, N.J. : Humana Press, ©2008.
Series:Methods in molecular biology (Clifton, N.J.) ; v. 414.
Subjects:
Carcinogenesis.
Apoptosis.
Cancer cells.
Tumors > Growth > Regulation.
Table of Contents:
  • Modulation of apoptosis to reverse chemoresistance / Gil Mor, Michele K. Montagna, and Ayesha B. Alvero
  • Caspase-3 activation is a critical determinant of genotoxic stress-induced apoptosis / Suparna Mazumder, Dragos Plesca, and Alexandru Almasan
  • Flow cytometry enumeration of apoptotic cancer cells by apoptotic rate / David Diaz [and others]
  • Detection of cancer-related proteins in fresh-frozen ovarian cancer samples using laser capture microdissection / Dan-Arin Silasi [and others]
  • Flow cytometric detection of activated caspase-3 / Richard Fox and Martine Aubert
  • The chemofx® assay : an ex vivo chemosensitivity and resistance assay for predicting patient response to cancer chemotherapy / Stacey L. Brower, Jeffrey E. Fensterer, and Jason E. Bush
  • Correlation of caspase activity and in vitro chemo-response in epithelial ovarian cancer cell lines / Ayesha B. Alvero, Michele K. Montagna, and Gil Mor
  • Assessing expression of apoptotic markers using large cohort tissue microarrays / Elah Pick, Mary M. McCarthy, and Harriet M. Kluger
  • Mitochondria potential, bax "activation," and programmed cell death / C. Michael Knudson and Nicholas M. Brown
  • In vitro and in vivo apoptosis detection using membrane permeant fluorescent-labeled inhibitors of caspases / Brian W. Lee [and others]
  • Caspase activity assays / Andrew L. Niles, Richard A. Moravec, and Terry L. Riss
  • Multiplex caspase activity and cytotoxicity assays / Andrew L. Niles, Richard A. Moravec, and Terry L. Riss
  • Homogeneous, bioluminescent proteasome assays / Martha A. O'Brien [and others]
  • A simple method for profiling mirna expression / Jia-Wang Wang and Jin Q. Cheng
  • Apoptotic caspase activation and activity / Jean-Bernard Denault and Guy S. Salvesen
  • Biochemical analysis of the native trail death-inducing signaling complex / Henning Walczak and Tobias L. Haas
  • Laser microdissection sample preparation for RNA analyses / Christopher J. Vega.

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