Effects of acetazolamide on physiologic and subjective responses of men to 14,000 feet / Richard S. Kronenberg, Stephen M. Cain.

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Bibliographic Details
Main Author: Kronenberg, Richard S.
Corporate Author: USAF School of Aerospace Medicine
Other Authors: Cain, Stephen M.
Format: Government Document Book
Language:English
Published: Brooks Air Force Base, TX : USAF School of Aerospace Medicine - Aerospace Medical Division (AFSC), 1967.
Series:SAM-TR ; 67-81.
Subjects:

MARC

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100 1 |a Kronenberg, Richard S. 
245 1 0 |a Effects of acetazolamide on physiologic and subjective responses of men to 14,000 feet /  |c Richard S. Kronenberg, Stephen M. Cain. 
260 |a Brooks Air Force Base, TX :  |b USAF School of Aerospace Medicine - Aerospace Medical Division (AFSC),  |c 1967. 
300 |a iii, 10 pages :  |b illustrations, tables ;  |c 27 cm. 
336 |a text  |b txt  |2 rdacontent. 
337 |a unmediated  |b n  |2 rdamedia. 
338 |a volume  |b nc  |2 rdacarrier. 
490 1 |a SAM-TR ;  |v 67-81. 
500 |a "September 1967." 
504 |a Includes bibliographical references. 
520 3 |a A study was carried out to determine the effectiveness of low doses of acetazolamide in ameliorating the symptoms of altitude sickness. Subjects were placed in a low pressure chamber at either 14,000 feet or 3,000 feet for 24 hours. Before entering the chamber each subject took a total of 750 mg of acetazolamide or a placebo. During their 24-hour stay, the subjects filled out a questionnaire designed to evaluate their state of well-being. Samples of arterial blood and cerebrospinal fluid were obtained and analyzed for pH, PO2, PCO2, CO2, HCO3, and lactate. Urine was analyzed for electrolytes and corticosteroids. The results indicated that pretreatment with acetazolamide was of sufficient clinical benefit to allow its recommendation prior to altitude exposure. 
650 0 |a Mountain sickness.  |0 http://id.loc.gov/authorities/subjects/sh85087808. 
650 0 |a Atmospheric pressure  |x Reduction.  |0 http://id.loc.gov/authorities/subjects/sh85009293. 
650 0 |a Acetazolamide.  |0 http://id.loc.gov/authorities/subjects/sh85000458. 
650 0 |a Carbonic anhydrase  |x Inhibitors. 
650 0 |a Anoxemia.  |0 http://id.loc.gov/authorities/subjects/sh85005466. 
650 0 |a Blood gases  |x Carbon dioxide. 
650 0 |a Blood gases  |x Oxygen. 
650 0 |a Pharmacology.  |0 http://id.loc.gov/authorities/subjects/sh85100599. 
650 2 |a Altitude Sickness. 
700 1 |a Cain, Stephen M. 
710 2 |a USAF School of Aerospace Medicine.  |0 http://id.loc.gov/authorities/names/n79120293  |1 http://isni.org/isni/0000000094055889. 
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952 f f |p Can circulate  |a University of Colorado Boulder  |b Boulder Campus  |c Norlin  |d Norlin Library - Government Information - US  |e D 301.26/13-6:67-81  |h Superintendent of Documents classification  |i document  |m U183070993980  |n 1