Heart failure management : the neural pathways / Edoardo Gronda, Emilio Vanoli, Alexandru Costea, editors.
This book describes the most recent insights into heart failure and the role played by autonomic nervous system pathophysiology in it, discussing the therapeutic implications. While current therapeutic approaches are able to control the effects of excessive adrenergic activation in heart failure syn...
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| Format: | eBook |
| Language: | English |
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Springer,
[2015]
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Table of Contents:
- Foreword; Contents; Part I: Current Heart Failure Therapies; 1: Introduction; References; 2: Therapies in Heart Failure, Tomorrow May Be Too Late; 2.1 The Heart Failure Pandemic and the "Halfway Technology" Swamp; 2.2 Current Heart Failure Therapy: The Achievements of Yesterday, the Hurdles of Today; 2.3 Heart Failure Therapy Tomorrow: Looking outside (Beyond) the Current Therapeutic Window; References; 3: Atrial Fibrillation, Heart Failure, and the Autonomic Nervous System; 3.1 Treatment of Atrial Fibrillation in the Heart Failure Population; 3.2 Autonomic Nervous System and AF.
- 3.3 Ganglionic Plexi: Autonomic Modulation in the Treatment of Atrial Fibrillation; 3.4 Renal Denervation; 3.5 Alternative Therapies for Neuromodulation; Conclusions; References; 4: Current Therapies for Ventricular Tachycardia: Are there Autonomic Implications of the Arrhythmogenic Substrate?; References; Part II: The Autonomic Regulation and Dis- regulation of the Heart: Pathophysiology in Heart Failure; 5: "The Autonomic Nervous System Symphony Orchestra": Pathophysiology of Autonomic Nervous System and Analysis of Activity Frequencies; 5.1 Introduction; 5.2 Methodologies.
- 5.2.1 General Considerations; 5.2.2 Muscle Sympathetic Nerve Activity (MSNA); 5.2.3 Heart Rate Variability; 5.2.3.1 Linear Analysis; 5.2.3.2 Nonlinear Analysis; 5.2.3.3 Symbolic Analysis; References; 6: Autonomic Pathophysiology After Myocardial Infarction Falling into Heart Failure; 6.1 Introduction; 6.2 The History; 6.3 Physiopathology of the Sympathetic Activation; 6.4 Nerve Sprouting After Myocardial Injury; 6.5 NGF Changes following an Ischemic Injury: From Short-Term to Long-Term Events; 6.6 From Acute Myocardial Injury to Chronic Heart Failure through Cardiac Remodeling.
- 6.7 Molecular Pathophysiology of Cardiac Sympathetic Innervation Conclusions; References; 7: Cardiovascular Serenade: Listening to the Heart; 7.1 Introduction; 7.2 Heart Rate Variability; 7.3 Intrathoracic Impedance Measurement; 7.4 Implantable Hemodynamic Monitoring; 7.5 CHAMPION Trial; 7.6 CHAMPION Trial Results: Benefits of Listening to Central Hemodynamic Data; Conclusions; References; 8: Whispering During Sleep: Autonomic Signaling During Sleep, Sleep Apnea, and Sudden Death; 8.1 The Cardiovascular System and Sleep Architecture.
- 9: Cerebral Aging: Implications for the Heart Autonomic Nervous System Regulation; 9.1 Central Control of Sympathetic Outflow; 9.2 Gangliar Level Control; 9.3 Nerve Ending Level: Presynaptic Control and Postsynaptic Signaling; 9.3.1 Presynaptic Control; 9.3.2 Postsynaptic Signaling; 9.4 The Baroreceptor Reflex; 9.5 Plasticity of the Autonomic Nervous System, the Role of Neurotrophins; References; Part III: Modulation of Autonomic Function in Heart Failure; 10: The Autonomic Cardiorenal Crosstalk: Pathophysiology and Implications for Heart Failure Management; 10.1 Introduction.