Myeloid leukemia [electronic resource] : methods and protocols / edited by Harry Iland, Mark Hertzberg, Paula Marlton.

The highly significant role that acquired genetic abnormalities play in the genesis, diagnosis, and management of hematological malignancies has become increasingly clear. Such abnormalities can serve as useful markers for initial diagnosis, accurate subclassification, and the evaluation of minimal...

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Bibliographic Details
Online Access: Full Text (via Springer)
Other Authors: Iland, Harry, Hertzberg, Mark, Marlton, Paula
Format: Electronic eBook
Language:English
Published: Totowa, N.J. : Humana Press, ©2006.
Series:Methods in molecular medicine ; 125.
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Table of Contents:
  • Isolation of RNA and DNA from leukocytes and cDNA synthesis / Joop H. Jansen and Bert A. van der Reijden
  • Cytogenetic and fish techniques in myeloid malignancies / Lynda J. Campbell
  • Overview of real-time RT-PCR strategies for quantification of gene rearrangements in the myeloid malignancies / Christophe Picard, Monique Silvy, and Jean Gabert
  • Diagnosis and monitoring of chronic myeloid leukemia by qualtitative and quantitative RT-PCR / Susan Branford and Tim Hughes
  • Detection of BCR-ABL mutations and resistance to imatinib mesylate / Susan Branford and Tim Hughes
  • Deletion of the derivative chromosome 9 in chronic myeloid leukemia / Lynda J. Campbell
  • Diagnosis and monitoring of PML-RARA-positive acute promyelocytic leukemia by qualitative RT-PCR / Vincenzo Rossi, Laura Levati, and Andrea Biondi
  • Diagnosis and monitoring of PML-RARA-positive acute promyelocytic leukemia by quantitative RT-PCR / Elisa Mokany [and others]
  • Diagnosis and monitoring of AML1MTG8 (ETO)-positive acute myeloid leukemia by qualitative and quantitative RT-PCR / Khalid Tobal and John A. Liu Yin
  • Diagnosis and monitoring of CBFB-MYH11-positive acute myeloid leukemia by qualitative and quantitative RT-PCR / Bert A. van der Reijden and Joop H. Jansen
  • Detection of the FIP1L1-PDGFRA fusion in idiopathic hypereosinophilic syndrome and chronic eosinophilic leukemia / Jan Cools, Elizabeth H. Stover, and D. Gary Gilliland
  • FLT3 mutations in acute myeloid leukemia / Hitoshi Kiyoi and Tomoki Naoe
  • WT-1 overexpression in acute myeloid leukemia and myelodysplastic syndromes / Daniela Cilloni, Enrico Gottardi, and Giuseppe Saglio
  • Classification of AML by DNA-oligonucleotide microarrays / Alexander Kohlmann [and others]
  • Classification of AML using a monoclonal antibody microarray / Richard I. Christopherson [and others]
  • Methods for the detection of the JAK2 V617F mutation in human myeloproliferative disorders / Peter J. Campbell [and others] Overexpression of PRV-1 gene in polycythemia rubra vera and essential thrombocythemia / Maurizio Martini, Luciana Teofili, and Luigi M. Larocca
  • Chimerism analysis following nonmyeloablative stem cell transplantation / Thomas Lion and Franz Watzinger.