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Membrane transporters [electronic resource] : methods and protocols / edited by Qing Yan.

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Membrane transporters and channels play key roles in drug absorption and distribution, influence drug efficacy and toxicity, and are the target of about 30% of currently marketed drugs. In Membrane Transporters: Methods and Protocols, a panel of recognized basic and clinical investigators-many world...

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Bibliographic Details
Online Access: Full Text (via Springer)
Other Authors: Yan, Qing, 1971-
Format: Electronic eBook
Language:English
Published: Totowa, NJ : Humana Press, 2003.
Series:Methods in molecular biology (Clifton, N.J.) ; v. 227.
Subjects:
Carrier proteins > Laboratory manuals.
Membrane proteins > Laboratory manuals.
Biological transport, Active > Laboratory manuals.
Ion channels > Laboratory manuals.
Biological transport, Active.
Carrier proteins.
Ion channels.
Membrane proteins.
Handbooks, manuals, etc.
Table of Contents:
  • Pharmacogenomics of membrane transporters an overview / Q. Yan
  • The iubmb-endorsed transporter classification system / W. Busch and M.H. Saier, Jr.
  • Bioinformatics and data integration in membrane transporter studies / Q. Yan
  • DNA microarrays to analyze gene expression in animals with altered transporter expression / G.W. Miller
  • Microarray data analysis in studies of membrane transporters / D. Hu
  • Laser capture microdissection to examine transporter expression in specific cell regions / O. Rho and G.W. Miller
  • Site-directed mutagenesis in the study of membrane transporters / R.M. Ryan, A.D. Mitrovic and R.J. Vandenberg
  • Fluorescence techniques for studying membrane transport proteins: The p-glycoprotein multidrug transporter / F.J. Sharom [and others]
  • Reconstitution of membrane transporters / F.J. Sharom and P.D. Eckford
  • Equilibrium binding and transport studies / A.M. Ojeda [and others]
  • Electrophysiological studies of ion channels and therapeutic potential with adenovirus-mediated gene transfer / J. Qu, T.V. Pham and M.N. Obreztchikova
  • Antibody production and immunocytochemical localization of amino acid transporters / D.V. Pow, R. Sullivan and H. Scott
  • Xenopus laevis oocytes / S. Broer
  • Measurement of intracellular ph / F.B. Loiselle and J.R. Casey
  • Small-angle x-ray scattering studies of membrane transporter peripheral components and soluble domains / B.H. Shilton
  • Membrane protein nmr studies / S.J. Opella
  • Analysis of soluble sugar permease domains by solution nmr / T.A. Wilkinson and Y. Chen
  • Molecular modeling and molecular dynamics simulations of membrane transporter proteins / D.S. Dwyer
  • Imaging plasma membrane proteins by confocal microscopy / S.W. Tsang and P.M. Haney.

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