Transplantation immunology [electronic resource] : methods and protocols / edited by Philip Hornick, Marlene Rose.
Technical innovations in the laboratory over the past ten years have greatly improved our understanding of the immunological mechanisms of transplanted organ rejection. In Transplantation Immunology: Methods and Protocols, leading experts in solid organ transplantation review the current status of t...
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| Online Access: |
Full Text (via Springer) |
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| Other Authors: | , |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Totowa, N.J. :
Humana Press,
©2006.
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| Series: | Methods in molecular biology (Clifton, N.J.) ;
v. 333. |
| Subjects: |
| Summary: | Technical innovations in the laboratory over the past ten years have greatly improved our understanding of the immunological mechanisms of transplanted organ rejection. In Transplantation Immunology: Methods and Protocols, leading experts in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods of utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The areas of tolerance induction and reprogramming of the immune system are also covered, along with a discussion of up-to-date methods of organ preservation, of today's optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection. State of the art and highly practical, Transplantation Immunology: Methods and Protocols illuminates for clinicians and scientists-both newcomers and experts-the new world of detecting and monitoring patients' immunological responses to solid organ transplantation. |
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| Physical Description: | 1 online resource (x, 429 pages) : illustrations. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 1588295443 9781588295446 9781597451222 1597451223 9781597450492 1597450499 |
| ISSN: | 1064-3745 ; |
| Source of Description, Etc. Note: | Print version record. |