The Golgi apparatus : state of the art 110 years after Camillo Golgi's discovery / Alexander A. Mironov and Margit Pavelka (eds.)

The Golgi apparatus is more than 110 years in the center of interest and scientific debates. It constitutes a main crossroads in secretory and endocytic traffic. However, despite thousands of details known about architecture, organization, and transport mechanisms across the Golgi stacks of cisterna...

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Bibliographic Details
Online Access: Full Text (via Springer)
Other Authors: Mironov, A. A. (Aleksandr Aleksandrovich), Pavelka, Margit, 1945-
Format: eBook
Language:English
Published: Wien ; New York : Springer, ©2008.
Subjects:
Table of Contents:
  • General considerations
  • The Golgi apparatus and main discoveries in the field of intracellular transport
  • The Golgi apparatus as a crossroads in intracellular traffic
  • Main machineries operating at the Golgi apparatus
  • SNAREs
  • Rabs
  • COPII
  • COPI: mechanisms and transport roles
  • Arfs and Arls: models for Arf family members in membrane traffic at the Golgi
  • COG complex
  • The TRAPP complex
  • The role of Ca2 in the regulation of intracellular transport
  • Golgi glycosylation enzymes
  • Nucleotide sugar transporters of the Golgi apparatus
  • Luminal lectins
  • The Golgi ribbon and the function of the Golgins
  • Functional cross talk between membrane trafficking and cell signalling
  • The role of the cytoskeleton in the structure and function of the Golgi apparatus
  • The dynamin-cortactin complex as a mediator of vesicle formation at the trans-Golgi network
  • The geometry of organelles of the secretory pathway
  • Main transport steps
  • ER-to-Golgi transport
  • Intra-Golgi transport
  • Structure and domain organization of the trans- Golgi network
  • Golgi-to-PM transport
  • Protein transport from the trans-Golgi network to endosomes
  • The transport of soluble lysosomal hydrolases from the Golgi complex to lysosomes
  • Transport of lysosomal membrane proteins from the Golgi complex to lysosomes
  • Retrograde endosome-to-TGN transport
  • Retrograde plasma membrane-to-Golgi apparatus transport
  • Interactions between endocytosis and secretory transport
  • Origins of the regulated secretory pathway
  • Secretion and endocytosis in endothelial cells
  • Formation of mucin granules
  • Golgi apparatus and epithelial cell polarity
  • Golgi apparatus inheritance
  • Peculiarities of intracellular transport in different organisms
  • Features of the plant Golgi apparatus
  • Yeast Golgi apparatus
  • Morphodynamics of the yeast Golgi apparatus
  • Structure and function of the Golgi organelle in parasitic protists
  • Evolution of the Golgi complex
  • General conclusions
  • Concluding remarks, questions, and perspectives.