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Inorganic controlled release technology : materials and concepts for advanced drug formulation / Xiang Zhang, Mark Cresswell.

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Inorganic Controlled Release Technology: Materials and Concepts for Advanced Drug Formulation provides a practical guide to the use and applications of inorganic controlled release technology (iCRT) for drug delivery and other healthcare applications, focusing on newly developed inorganic materials...

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Bibliographic Details
Online Access: Full Text (via ScienceDirect)
Main Authors: Zhang, Xiang (Author), Cresswell, Mark (Author)
Format: eBook
Language:English
Published: Oxford, UK : Elsevier : BH, [2016]
Subjects:
Controlled release technology.
Table of Contents:
  • Front Cover
  • Inorganic Controlled Release Technology: Materials and Concepts for Advanced Drug Formulation
  • Copyright
  • Contents
  • About the Author
  • Preface
  • Acknowledgments
  • Key Features
  • Chapter 1: Materials for Inorganic Controlled Release Technology
  • 1.1. Introduction
  • 1.2. Comparison between Organic and Inorganic CRT
  • 1.3. Materials Chemistry and Processing Technology
  • 1.3.1. Fusion-Based Approach to Making Water-Soluble Glasses
  • 1.3.2. Sol-Gel Approach
  • 1.3.3. Surfactant Template Approach for Mesoporous Silica.
  • 1.4. Materials Physics and Drug-Loaded Micro/NanostructureReferences
  • Chapter 2: Materials Fundamentals of Drug Controlled Release
  • 2.1. Introduction of Materials Nanostructure
  • 2.1.1. The Structure of Amorphous Materials
  • 2.1.2. Theories of Amorphous Materials
  • 2.1.2.1. Glass Transition
  • 2.1.2.2. Free Volume Theory
  • 2.2. API Distribution Within Inorganic Matrices
  • 2.2.1. Traditional API Distribution
  • 2.2.2. API Distribution Within inorganic CRT Matrices
  • 2.3. Basic Understanding of Potential Molecular Interactions.
  • 2.3.1. Classical API Excipients2.3.2. Interactions Between API and inorganic CRT Matrix Systems
  • 2.3.3. The Surface Chemistry of Silica
  • 2.3.4. Molecular Interaction with Directionally Templated Mesoporous Silica Systems
  • 2.3.5. Towards Molecular Dispersion and Distribution
  • 2.3.6. Molecular Interaction Sites on Sol-Gel Silica and Phosphate Glass
  • 2.3.7. Dissolution of Phosphate Glass
  • 2.3.8. Glass Formulation for inorganic CRT
  • 2.4. Theory and Practical Modelling of Drug Controlled Release Kinetics
  • References
  • Further Reading.
  • Chapter 3: Materials Characterization of Inorganic Controlled Release3.1. Introduction
  • 3.2. Chemical Analysis
  • 3.2.1. X-Ray Fluorescence
  • 3.2.1.1. Case Study: Contamination Investigation
  • 3.2.2. Inductively Coupled Plasma Mass Spectrometry
  • 3.2.2.1. Case Study: Controlled Release of Strontium from P-glass
  • 3.2.2.2. Case Study: Detection of Cobalt and Chromium Ions in Patients with Metal-on-Metal Implants
  • 3.2.3. FTIR
  • 3.2.3.1. Case Study: FTIR Study of Silanol Groups in Silica, Slica-Alumina, and Zeolites.
  • 3.2.3.2. Case Study: Quantification of Bridging and Non-bridging SiO as a Function of SiO2 % by FTIR3.2.4. X-Ray Photoelectron Spectroscopy (XPS)-Surface Chemistry 1
  • 3.2.4.1. Case Study: XPS Study on SiOSi Bridging Energy Variation
  • 3.2.5. Secondary Ion Mass Spectrometry (SIMS)-Surface Chemistry 2
  • 3.2.5.1. Case Study: Investigation of the Surface Chemistry of a Bioglass-Polymer Hybrid Composite
  • 3.3. Physical Property Analysis
  • 3.3.1. X-Ray Diffraction
  • 3.3.1.1. Case Study: Characterization of a Calcium Hydroxyapatite Reference Material5.

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