Inflammation in the pathogenesis of chronic diseases [electronic resource] : the COX-2 controversy / edited by Randall E. Harris.

Discusses the role of inflammation in the pathogenesis of major chronic diseases and the controversy regarding risk versus benefit of selective cyclooxygenase-2 (COX-2) inhibitors. This volume is intended for scientists in medicine, epidemiology, pharmacology, molecular biology, and related fields.

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Bibliographic Details
Online Access: Full Text (via Springer)
Other Authors: Harris, Randall E.
Format: Electronic eBook
Language:English
Published: New York : Springer, ©2007.
Series:Sub-cellular biochemistry ; v. 42.
Subjects:
Table of Contents:
  • Historical perspectives. Anti-inflammatory drugs in the 21st century / K.D. Rainsford
  • Inflammatory mechanisms of pathogenesis. Nitric oxide synthase and cyclooxygenase interactions in cartilage and meniscus: relationships to joint physiology, arthritis, and tissue repair / J. Brice Weinberg, Beverley Fermor, Farshid Guilak
  • Obesity, inflammation, and vascular disease: the role of the adipose tissue as an endocrine organ / Paolo Calabro', Edward T.H. Yeh
  • Cyclooxygenase-2 (COX-2) and the inflammogenesis of cancer / Randall E. Harris
  • Role of COX-2 in inflammatory and degenerative brain diseases / Luisa Minghetti
  • Inflammation and Cardiovascular Disease: the Coxib Controversy. Cardiovascular effects of the selective cyclooxygenase-2 inhibitors / William B. White
  • COX-2 inhibitors and Cardiovascular Risk / Daniel J. Salzberg, Matthew R. Weir
  • A biological rationale for cardiotoxic effects of rofecoxib: comparative analysis with other COX-2 selective agents and NSAIDs / R. Preston Mason [and others]
  • COX-2 Blockade in cancer prevention and therapy. Cancer chemoprevention by COX-2 blockade: results of case control studies / Randall E. Harris, Joanne Beebe-Donk, Galal A. Alshafie
  • Strategies for colon cancer prevention: combination of chemopreventive agents / Bandaru S. Reddy
  • Inflammation and neurodegenerative disease. NSAIDs for the chemoprevention of Alzheimer's disease / Christine A. Szekely, Terrence Town, Peter P. Zandi
  • Inflammation in Parkinson's disease: causative or epiphenomenal? / Andreas Hald, Johan van Beek, and Julie Lotharius
  • Nutrition, inflammation and chronic disease. Essential polyunsaturated fatty acids, inflammation, atherosclerosis and cardiovascular dieseases / Michel de Logeril
  • Nutritional interventiion in brain aging: reducing the effects of inflaammation and oxidative stress / Frances C. Lau, Barbara Shukitt-Hale, James Joseph.