Glycosylation engineering of biopharmaceuticals : methods and protocols / edited by Alain Beck.
Glyco-engineering is being developed as a method to control the composition of carbohydrates and to enhance the pharmacological properties of monoclonal antibodies (mAbs) and other proteins. In Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols, experts in the field provide reade...
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| Online Access: |
Full Text (via Springer) |
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| Other Authors: | |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
New York :
Humana : Springer,
©2013.
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| Series: | Methods in molecular biology (Clifton, N.J.) ;
v. 988. |
| Subjects: |
| Summary: | Glyco-engineering is being developed as a method to control the composition of carbohydrates and to enhance the pharmacological properties of monoclonal antibodies (mAbs) and other proteins. In Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols, experts in the field provide readers with production and characterization protocols of glycoproteins and glyco-engineered biopharmaceuticals with a focus on mAbs. The volume is divided in four complementary parts dealing with glyco-engineering of therapeutic proteins, glycoanalytics, glycoprotein complexes characterization, and PK/PD assays for therapeutic antibodies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols serves as an ideal guide for scientists striving to push forward the exciting field of engineered biopharmaceuticals. |
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| Physical Description: | 1 online resource (xv, 355 pages) : illustrations |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 9781627033275 1627033270 1627033262 9781627033268 |
| ISSN: | 1940-6029 ; |
| Language: | English. |
| Source of Description, Etc. Note: | Print version record. |