Arsenic contamination in the environment [electronic resource] : the issues and solutions / Dharmendra Kumar Gupta, Soumya Chatterjee, editors.
This book provides an overview to researchers, graduate, and undergraduate students, as well as academicians who are interested in arsenic. It covers human health risks and established cases of human ailments and sheds light on prospective control measures, both biological and physico-chemical. Arse...
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Format: | Electronic eBook |
Language: | English |
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Springer,
2017.
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Table of Contents:
- Dedication; Foreword; Preface; Contents; Contributors; About the Editors; Arsenic Contamination from Historical Aspects to the Present; 1 Introduction; 2 Historical Uses of Arsenic; 3 Different Sources of Arsenic in the Environment; 4 Some Epidemiological Studies of Arsenic Exposure from Water/Food Sources; 5 Toxic Effects of Arsenic; 6 Metabolic Pathway of Arsenic; 7 Remediation Measures and Recommendations for Arsenic Decontamination; 8 Conclusion; References; Arsenic: Source, Occurrence, Cycle, and Detection; 1 Introduction to Arsenic: Its Sources and Occurrence in the Environment.
- 2 Properties of Arsenic and Its Different Species3 Organic Arsenic Compounds; 4 Arsenic Sinks and Iron Oxides; 5 Volatile Arsenicals; 6 Arsenic Biogeochemical Cycle; 7 Environmental Transport and Distribution; 8 Arsenic Kinetics and Metabolism; 9 Arsenic Volatilization by Microorganisms; 9.1 Fungi; 9.2 Bacteria; 9.3 Methanoarchaea; 9.4 Other Eukaryotic Microorganisms; 10 Analytical Methods for Arsenic Detection; 10.1 Sample Preparation and Treatment; 10.2 Atomic Spectrometry-Based Methods; 10.3 Electrochemical Detection; 10.4 Radiochemical Methods; 10.5 X-Ray Spectroscopy; 11 Conclusion.
- 9.2 Arsenic-Induced Epigenetic Alterations and Aberrant DNA Methylation9.3 Arsenic and Micro-RNA Expression; 10 Development of Cancer: Receptors and Signaling Pathways; 10.1 PI3K/AKT Signaling Pathway; 10.2 Nrf2-KEAP1 Signaling Pathway and Arsenic; 11 Therapeutic Applications of Arsenic; 11.1 Application on Acute Promyelocytic Leukemia (APML, APL); 11.2 Arsenic and Chronic Myelogenous Leukemia (CML) Treatment; 11.3 Arsenic Therapy in Other Malignancies; 11.4 Genetic Susceptibility; 12 Conclusion; References; Epigenetics in Arsenic Toxicity: Mechanistic Response, Alterations, and Regulations.
- 1 Introduction2 Epigenetic Regulation and Alterations in Animal and Human System During Mechanistic Response of Cellular As Toxicity; 2.1 DNA Methylation and As Toxicity; 2.1.1 Modulation of Global DNA Methylation Footprint Under As Exposure; 2.1.2 As Toxicity, Gene-Specific DNA Methylation and Tumorigenesis/Oncogenesis; 2.1.3 As-Induced Hypomethylation in Gene Promoters; 2.1.4 As-Induced Hypermethylation in Gene Promoters; 2.2 Histone Modifications Under As Toxicity; 2.2.1 Histone Acetylation Under As Exposure; 2.2.2 Histone Methylation During As Exposure.