Stereoselective synthesis of drugs and natural products / edited by Vasyl Andrushko, Natalia Andrushko, Karlsruhe, Germany.
Saved in:
| Online Access: |
Full Text (via ProQuest) |
|---|---|
| Other Authors: | , |
| Format: | eBook |
| Language: | English |
| Published: |
Hoboken, New Jersey :
Wiley,
[2013]
|
| Subjects: |
Table of Contents:
- V. 1. Part I: general methods and strategies
- Principles, concepts, and strategies of stereoselective synthesis
- Chiral auxiliaries in drug synthesis
- Solid-phase organic synthesis of drugs and natural products
- Asymmetric phase-transfer catalysis
- Microwave-assisted stereoselective synthesis
- Application of microreactor methodology for organic synthesis
- Part II: stereoselective synthesis by bond formation
- Stereoselective methods for C-C bond formation
- Asymmetric [alpha]-alkylation of aldehydes, ketones, and carboxylic acids
- Asymmetric aldol reactions in the total syntheses of natural products
- Asymmetric michael addition and related reactions
- Construction of polypropionate fragments in natural product synthesis
- Organocatalytic conjugate addition in stereoselective synthesis
- Stereoselective nozaki-hiyama-kishi reaction
- Transition-metal-catalyzed asymmetric C-C cross-couplings in stereoselective synthesis
- Asymmetric hydroformylation, hydroxycarbonylation, and alkoxycarbonylation for stereoselective synthesis
- Intramolecular oxycarbonylation in stereoselective synthesis
- Stereoselective cycloaddition reactions
- Sigmatropic rearrangements in stereoselective synthesis
- Ring contraction reactions in the total synthesis of biologically active natural products
- Electrocyclic reactions in stereoselective synthesis
- Transannular cyclization in natural product total synthesis
- Cascade reactions in stereoselective synthesis
- Sulfur dioxide: a powerful tool for the stereoselective construction of c-c bonds
- Transition metal c-h activation: application to stereoselective synthesis of natural products and drugs
- Metathesis reactions in drug and natural product synthesis
- Radicals in stereoselective C-C bond formation
- Trifluoromethyl (CF3) group insertion methods in stereoselective synthesis
- Stereoselective organocatalyzed C-C bond-forming reactions
- Enzyme-catalyzed stereoselective C-C bond formation reactions in total syntheses.
- V.2. Stereoselective methods for C-H bond formation
- Stereoselective hydrogenation of C=C bonds: application to drug and natural product synthesis
- Asymmetric hydrogenation of C=O and C=N bonds in stereoselective synthesis
- Asymmetric protonation of carbanions and polar double bonds: application to total syntheses
- Organocatalytic reduction in stereoselective synthesis
- Biocatalytic asymmetric reduction of C=O and activated C=C bonds in stereoselective synthesis
- Stereoselective methods for C-O bond formation
- Transition-metal-catalyzed stereoselective oxidations in drug and natural product synthesis
- Asymmetric epoxidation in stereoselective synthesis
- Biocatalytic asymmetric oxidations in stereoselective synthesis
- Ether transfer methodology: application to the synthesis of polyketide natural products
- Stereoselective formation of 2-deoxyglycosidic bonds in biologically active natural products
- Stereoselective methods for C-N Bond formation
- Asymmetric hydroamination and reductive amination in total synthesis
- Carboamination and alkylative cyclization with C-N bond formation in stereoselective syntheses
- Cycloadditions with stereoselective C-N bond formation in total syntheses
- Stereoselective formation of other C-heteroatomand other bonds
- Stereoselective halogenations
- Stereoselective synthesis of halogenated natural products
- Asymmetric fluorination methods: application in the stereoselective synthesis of fluorinated drugs
- Enzymatic halogenation in stereoselective synthesis
- Stereoselective carbon-sulfur (C-S) bond formation
- Stereoselective methods for carbon-phosphorus (C-P) bond formation
- Transition-metal-catalyzed asymmetric sulfoxidation in drug and natural product synthesis
- Part III: methods of analysis and chiral separation
- NMR spectroscopy in drug and natural product analysis
- Determination of enantiomeric purity and absolute configuration by NMR spectroscopy
- Solid-state NMR spectroscopy in drug design and discovery
- Capillary electrophoresis in chiral separations
- Determination of absolute configuration using chiroptical methods
- Chiral chromatographic methods in the analysis and purification of enantiomers
- X-ray crystallography and 1H NMR anisotropy methods for determination of absolute configurations
- Crystallization-based separation of enantiomers
- Enzymatic dynamic kinetic resolution in stereoselective synthesis.