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|a 951065345
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|a GWRE
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|a Q325.5
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|a Ping Chiu, Kuo,
|e author.
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|a Next-generation sequencing and sequence data analysis /
|c Kuo Ping Chiu.
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|a Sharjah :
|b Bentham Science Publisher,
|c [2016]
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| 300 |
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|a 1 online resource.
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|a text
|b txt
|2 rdacontent.
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|a computer
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|2 rdamedia.
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|a online resource
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|a Includes bibliographical references and index.
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|a FOREWORD ; PREFACE ; ACKNOWLEDGEMENTS ; CONFLICT OF INTEREST; Background Introduction ; The Ultimate Frontier of Knowledge: the Myster-ious Genomes and the Gene Expression and Regul-ation in the Upstream of Biological Information Flow ; INTRODUCTION; MICROSCOPIC STRUCTURE AND ORGANIZATION OF INFORMATION MOLECULES; THE STRUCTURE AND ORGANIZATION OF INFORMATION MOLECULES AT THE MOLECULAR LEVEL; DNA is the Most Magnificent Molecule Selected By Evolution ; DNA Packaging; Nucleosome; GENE EXPRESSION AND REGULATION IN THE EUKARYOTIC SYSTEM.
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|a A. ATP-Dependent and ATP-Independent Chromatin Remodeling EnzymeB. X Chromosome Inactivation; C. Pathway Flow from Extracellular Signal to the Nucleus; D. TFs, Motifs, and DNA-Protein Interaction; E. Transcription Factories (TFs); F. Epigenetic Modifications; G. Alternative Splicing; H. MicroRNA (miRNA); THE BOTTOM LINE; REFERENCES; Evolution of DNA Sequencing Technologies ; INTRODUCTION; CHARACTERISTICS OF DNA SEQUENCING; ADVANCES IN SEQUENCING TECHNOLOGIES; MANUAL SANGER SEQUENCING; AUTOMATED SANGER SEQUENCING ; KEY CHANGES FROM MANUAL TO AUTOMATED SANGER SEQUE-NCING.
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|a THE NEXT-GENERATION SEQUENCING SINGLE MOLECULE SEQUENCING; REFERENCES; Mechanisms of Next-Generation Sequencing (NGS) ; INTRODUCTION; Changes Made From Automated Sanger Sequencing to Next-Gen Sequencing; In situ PCR for Clonal Amplification of Templates; NGS Sequencing Mechanisms; I. Sequencing-By-Synthesis; Solexa Sequencers Manufactured By Illumina -- HiSeq 2000 as an Example (Fig. 1); Sequencing Library Preparation ; 454 Sequencers By Roche ; Sequencing Library Preparation; Sequencing-By-Synthesis on Picotiter Plate.
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|a II. Sequencing By Ligation: SOLiD Sequencers (Fig. 8) Manufactured By Life Technologies Inc. REFERENCES; Genome Assembly, the Genomic Era and the Rise of the Omics Era ; INTRODUCTION; PART I. REVIEW OF THE STRATEGIES EMPLOYED FOR GENOME ASSEMBLY; Technological impacts on genome assembly; Next-Generation Sequencing (NGS); Oligo-mediated technologies ; PART II. THE GENOMIC ERA; The Human Genome Project; Genomic Era; Post Genomic Era; KEY EVENTS LEADING TO THE DEVELOPMENT OF THE GENOMIC ERA ; GENERAL PROCEDURE FOR RESEQUENCING; ADVANTAGES OF DIRECT MAPPING AGAINST A REFERENCE (NORMAL) GENOME.
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|a PART III. THE RISE OF THE OMICS ERAThe Omics Era; REFERENCES; Application of DNA Sequencing in Biological Investigations ; Laboratory Setup and Fundamental Works ; INTRODUCTION; I. WETLAB; Setting up a Wetlab; Protocols to Use; II. DRYLAB ; Setting Up a Drylab; Sequence Data Processing; Methods Used for Sequence Data Processing and Analysis; REFERENCES; Sequencing Libraries and Basic Procedure for Sequencing Library Construction ; INTRODUCTION; CLASSIFICATION OF SEQUENCING LIBRARIES; GENERAL PROCEDURE FOR SEQUENCING LIBRARY CONSTRUCTION.
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|a Online resource; title from PDF title page (EBSCO, viewed January 25, 2016)
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| 650 |
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|a Machine learning.
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| 650 |
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|a Data mining.
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| 650 |
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|a Computational intelligence.
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| 650 |
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|a Computational intelligence.
|2 fast
|0 (OCoLC)fst00871995.
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| 650 |
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|a Data mining.
|2 fast
|0 (OCoLC)fst00887946.
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| 650 |
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|a Machine learning.
|2 fast
|0 (OCoLC)fst01004795.
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| 776 |
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|i Print version:
|a Chiu, Author: Kuo Ping.
|t Next-Generation Sequencing and Sequence Data Analysis.
|d Sharjah : Bentham Science Publishers, ©2015
|z 9781681080932.
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| 856 |
4 |
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|u https://ebookcentral.proquest.com/lib/ucb/detail.action?docID=4412587
|z Full Text (via ProQuest)
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|a .b97344953
|b 02-20-23
|c 10-03-17
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|b Ebook Central Academic Complete
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|a University of Colorado Boulder
|b Online
|c Online
|d Online
|e Q325.5
|h Library of Congress classification
|i web
|n 1
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