Platinum-based drugs in cancer therapy / edited by Lloyd R. Kelland and Nicholas P. Farrell.
In Platinum-Based Drugs in Cancer Therapy, leading international experts comprehensively review all aspects of platinum anticancer drugs and their current use in treatment, as well as examining their future therapeutic prospects. Writing from a variety of disciplines, these authorities discuss the c...
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| Online Access: |
Full Text (via EBSCO) |
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| Other Authors: | , |
| Format: | eBook |
| Language: | English |
| Published: |
Totowa, N.J. :
Humana Press,
©2000.
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| Series: | Cancer drug discovery and development ;
7. |
| Subjects: |
Table of Contents:
- I: Platinum Chemistry
- 1 The Chemistry of Cisplatin in Aqueous Solution
- 2 Chemistry and Structural Biology of 1,2-Interstrand Adducts of Cisplatin
- 3 Transplatin-Modified Oligonucleotides as Potential Antitumor Drugs
- II: Platinum Biochemistry
- 4 Cisplatin Accumulation
- 5 Cisplatin Resistance in Ovarian Cancer: Mismatch Repairand Engagement of Apoptosis
- 6 DNA Adduct Tolerance and Bypass
- 7 How Does Cisplatin Kill Cells?
- III: Clinical Antitumor Activity and Toxicology of Platinum Drugs
- 8 Clinical Experience with Cisplatin and Carboplatin
- 9 Clinical Experience: Platinum and Taxanes
- 10 Clinical Experience: DACH-Based Platinum Drugs
- 11 Clinical Toxicology of Platinum-Based Cancer Chemotherapeutic Agents
- 12 Toxicology and Regulatory Aspects of Platinum Drugs
- IV: New Platinum Drugs of the Future
- 13 New Platinum Drugs: The Pathway to Oral Therapy
- 14 Polynuclear Charged Platinum Compounds as a New Class of Anticancer Agents: Toward a New Paradigm.