Metalloprotein active site assembly / editors, Michael K. Johnson, University of Georgia, Athens, GA, USA, Robert A. Scott, University of Georgia, Athens, GA, USA.
Summarizes the essential biosynthetic pathways for assembly of metal cofactor sites in functional metalloproteins Metalloprotein Active Site Assembly focuses on the processes that have evolved to orchestrate the assembly of metal cofactor sites in functional metalloproteins. It goes beyond the simpl...
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Format: | Electronic eBook |
Language: | English |
Published: |
Chichester, West Sussex :
Wiley,
2017.
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Series: | EIC books
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Table of Contents:
- Title Page; Copyright; Table of Contents; Encyclopedia of Inorganic and Bioinorganic Chemistry; Contributors; Series Preface; Volume Preface; Periodic Table of the Elements; Part 1: Assembly and Trafficking of Simple Fe-S Clusters; Nif System for Simple [Fe-S] Cluster Assembly in Nitrogen-Fixing Bacteria; 1 Introduction; 2 The Nif System as a Model for Analysis of Simple [Fe-S] Cluster Assembly; 3 Analysis of the Mo-Dependent Nitrogen-Fixing System in A. vinelandii; 4 Genetic Phenotypes and Biochemical Features Indicated a Role for NifU and NifS in [Fe-S] Cluster Formation
- 5 NifS Cysteine Desulfurase6 NifU Provides a Scaffold for [Fe-S] Cluster Assembly; 7 NifU and NifS as the Minimum Set for the Assembly and Transfer of Fe-S Clusters; 8 The NifS/NifU [Fe-S] Cluster Assembly Toolkit Provides a Paradigm for Simple [Fe-S] Cluster Assembly; 9 Functional Cross Talk Between [Fe-S] Cluster Biosynthetic Systems; 10 Concluding Remarks; 11 Acknowledgments; 12 Related Articles; 13 Abbreviations and Acronyms; 14 References; Iron-Sulfur Cluster Assembly in Bacteria and Eukarya using the ISC Biosynthesis Machinery; 1 Introduction; 2 Core Fe-S Cluster Assembly Step
- 3 Fe-S Cluster Transfer Step4 From the Mitochondria to the Cytosol; 5 Unsolved Questions; 6 Related Articles; 7 Abbreviations and Acronyms; 8 References; The Suf System in Archaea, Bacteria, and Eukaryotic Organelles; 1 Introduction; 2 Bacterial Suf Pathways: Diverse Roles in Fe-S Cluster Biogenesis; 3 Archaea and the Origin of the Suf Pathway; 4 Eukaryotic Suf Systems: A Role for Suf in Plastid Organelles and in the Cytoplasm; 5 Conclusions; 6 Related Articles; 7 Abbreviations and Acronyms; 8 References; Roles of Class II Glutaredoxins in the Maturation of Fe-S Proteins; 1 Introduction
- 2 The Cellular Maturation of Fe-S Proteins in Model Organisms3 Involvement of Glutaredoxins in the Maturation of Fe-S Proteins in Eukaryotes; 4 Spectroscopic and Structural Data for Fe-S Bridged Complexes Involving Class II GRXs; 5 Molecular Interactions Between Class II GRXs and their Partners; 6 Conclusions; 7 Related Articles; 8 Abbreviations and Acronyms; 9 References; Part 2: Assembly of Complex and Heterometallic Fe-S Cluster Active Sites; Nitrogenase Metallocluster Assembly; 1 Introduction; 2 Properties of NifDK Metalloclusters; 3 Biosynthetic Factors; 4 M-Cluster Biosynthesis
- 5 Biosynthesis of P Cluster6 Discussion and Future Directions; 7 Acknowledgments; 8 Related Articles; 9 Abbreviations and Acronyms; 10 References; Metallocluster Assembly: Maturation of [FeFe]-Hydrogenases; 1 Introduction; 2 The Metal Center of [FeFe]-Hydrogenases; 3 A Protein Machinery for [FeFe]-Hydrogenase Maturation; 4 The Hyd Proteins; 5 Mechanism of Maturation of [FeFe]-Hydrogenases; 6 Maturase-Free Chemical Maturation: A Unique Technological Tool; 7 Conclusions; 8 Acknowledgments; 9 Abbreviations and Acronyms; 10 References; CO Dehydrogenase and Acetyl-CoA Synthase; 1 Introduction