Cover Image

Genetics of bone biology and skeletal disease / edited by Rajesh V. Thakker [and 3 others]

Show other versions (1)

"[This book] is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling...

Full description

Saved in:
Bibliographic Details
Online Access: Full Text (via ScienceDirect)
Other Authors: Thakker, R. V. (Editor)
Format: eBook
Language:English
Published: London ; Waltham, MA : Academic Press, [2018]
Edition:Second edition.
Subjects:
Bones > Diseases > Genetic aspects.
Electronic book.
Table of Contents:
  • 1: GENERAL BACKGROUND TO GENETICS
  • Chapter 2
  • Epigenetics
  • Chapter 3
  • Genome-Wide Association Studies
  • Chapter 4
  • Copy Number Variation
  • Chapter 5
  • Genomic Profiling in Bone
  • Chapter 6
  • Functional Genomics
  • Chapter 7
  • Mouse Models: Approaches to Generate In Vivo Models for Hereditary Disorders of Mineral and Skeletal Homeostasis
  • Chapter 8
  • Prospects of Gene Therapy for Skeletal Diseases
  • Chapter 9
  • Pharmacogenetics and Pharmacogenomics of Osteoporosis: Personalized Medicine Outlook
  • Chapter 10
  • Genetic Testing and Counseling
  • 2: GENERAL BACKGROUND TO BONE BIOLOGY
  • Chapter 11
  • Biology of Bone and Cartilage
  • Chapter 12
  • Overview of Bone Structure and Strength
  • Chapter 13
  • Overview of Joint and Cartilage Biology
  • Chapter 14
  • Osteocyte Biology
  • Chapter 15
  • Skeletal Stem Cells/Bone Marrow Stromal Cells
  • Chapter 16
  • Osteoimmunology
  • Chapter 17
  • Integrating Endocrine and Paracrine Influences on Bone; Lessons From Parathyroid Hormone and Parathyroid Hormone-Related Protein
  • Chapter 18
  • Genetics of Bone Fat and Energy Regulation
  • Chapter 19
  • The Cross Talk Between the Central Nervous System, Bone, and Energy Metabolism
  • Chapter 20
  • Fetal Control of Calcium and Phosphate Homeostasis
  • Chapter 21
  • Control of Mineral and Skeletal Homeostasis During Pregnancy and Lactation
  • Chapter 22
  • Osteoporosis Genes Identified by Genome-Wide Association Studies
  • Chapter 23
  • Osteogenesis Imperfecta
  • Chapter 24
  • Osteoarthritis: Genetic Studies of Monogenic and Complex Forms
  • Chapter 25
  • Genetics of Paget's Disease of Bone
  • Chapter 26
  • Mendelian Disorders of RANKL/OPG/RANK/NF-κB Signaling
  • Chapter 27
  • Skeletal Dysplasias
  • Chapter 28
  • Hypophosphatasia and How Alkaline Phosphatase Promotes Mineralization
  • Chapter 29
  • Sclerosing Bone Disorders
  • Chapter 30
  • Fibrodysplasia (Myositis) Ossificans Progressiva
  • Chapter 31
  • Thyroid Hormone in Bone and Joint Disorders
  • Chapter 32
  • Disorders and Mechanisms of Ectopic Calcification
  • 4: PARATHYROID AND RELATED DISORDERS
  • Chapter 33
  • Hyperparathyroidism
  • Chapter 34
  • Hypoparathyroidism
  • Chapter 35
  • Gsα, Pseudohypoparathyroidism, Fibrous Dysplasia, and McCune-Albright Syndrome
  • Chapter 36
  • Genetic Disorders Caused by Mutations in the PTH/PTHrP Receptor, its Ligands, and Downstream Effector Molecules
  • Chapter 37
  • Genetically Determined Disorders of Extracellular Calcium (Cao2+) Sensing and Cao2+ Homeostasis
  • Chapter 38
  • Multiple Endocrine Neoplasia Syndromes
  • 5: VITAMIN D AND RENAL DISORDERS
  • Chapter 39
  • Genetic Disorders Of Vitamin D Synthesis and Action
  • Chapter 40
  • Heritable Renal Phosphate Wasting Disorders
  • Chapter 41
  • Renal Fanconi Syndrome, Dent Disease, and Bartter Syndrome
  • Chapter 42
  • Inherited Magnesium Disorders
  • Chapter 43
  • Genetic Hypercalciuria: A Major Risk Factor in Kidney Stones.

Similar Items