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230820s2023 ne ob 001 0 eng d |
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20231006013431.2 |
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|a (OCoLC)scd1394114914
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|a scd9780443190940
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|a 1394118865
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|a 9780443153044
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|z 9780443190940
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|a (OCoLC)1394114914
|z (OCoLC)1394118865
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|a RS431.A64
|b D54 2023
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| 049 |
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|a GWRE
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| 245 |
0 |
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|a Dihydropyrimidinones as potent anticancer agents :
|b medicinal chemistry perspective /
|c edited by Mashooq Ahmad Bhat, Muneeb U. Rehman, Amita Verma.
|
| 264 |
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1 |
|a Amsterdam, Netherlands ;
|a Cambridge, MA :
|b Elsevier,
|c [2023]
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| 300 |
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|a 1 online resource (xiii, 279 pages)
|
| 336 |
|
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
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| 504 |
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|a Includes bibliographical references and index.
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0 |
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|a Front Cover -- Dihydropyrimidinones as Potent Anticancer Agents -- Copyright Page -- Contents -- List of contributors -- 1 Introduction of dihydropyrimidinones: a medicinal chemistry perspective -- 1.1 Introduction -- 1.2 History -- 1.3 Separation of isomers -- 1.4 Synthesis -- 1.4.1 Chemistry and biological activities -- 1.4.2 New derivative: biphenyl dihydropyrimidinone -- 1.5 Future perspective -- 1.6 Conclusion -- References -- 2 Synthetic strategies of dihydropyrimidinones -- 2.1 Introduction -- 2.2 Synthetic strategies for dihydropyrimidinones
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|a 2.2.1 Classical methods to synthesize dihydropyrimidinones -- 2.2.2 Nonclassical methods to synthesize dihydropyrimidinones -- 2.2.2.1 Microwave-assisted synthesis -- 2.2.2.2 Ultrasonication-assisted synthesis -- 2.2.2.3 Synthesis using ionic liquids as catalysts -- 2.2.2.4 Synthesis using nanomaterial-assisted catalysts -- 2.2.2.5 Synthesis under green conditions and chiral catalysts -- 2.2.2.6 Synthesis using miscellaneous strategies -- 2.3 Conclusion -- References -- 3 Biological activities of dihydropyrimidinones -- 3.1 Introduction -- 3.1.1 Antiinflammatory activity
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| 505 |
8 |
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|a 4.2 Synthetic strategies -- 4.3 Pharmacological potential of dihydropyrimidinones -- 4.3.1 Antifilarial activity -- 4.3.2 Antitubercular activity -- 4.3.3 Antihypertensive activity -- 4.3.4 Antibacterial activity -- 4.3.5 Anticancer activity -- 4.3.6 Antiinflammatory activity -- 4.3.7 Anti-HIV -- 4.3.8 Analgesic activity -- 4.3.9 Antifungal activity -- 4.3.10 Antihyperglycemic activity -- 4.3.11 Antisevere acute respiratory syndrome activity -- 4.3.12 Antioxidant activity -- 4.3.13 Anticonvulsant activity -- 4.3.14 Anti-Alzheimer's activity -- 4.3.15 Antihepatitis activity -- 4.4 Conclusion
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|a Acknowledgment -- Conflict of interest -- Funding -- References -- 5 Dihydropyrimidinones scaffold and potential anticancer targets -- 5.1 Introduction -- 5.2 Biological activities -- 5.2.1 Anticancer properties -- 5.2.2 Dihydropyrimidin-2(1H)-one (or thione) scaffolds potent against different cancers -- 5.2.2.1 Diarylpyrazole-ligated dihydropyrimidinones are potent scaffolds against breast cancer -- 5.2.2.1.1 Dihydropyrimidinone-based scaffolds are effective against breast cancer -- 5.2.2.1.2 DHPM-based scaffolds block kinesin Eg5
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| 588 |
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|a Description based on online resource; title from digital title page (viewed on September 21, 2023).
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| 650 |
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|a Antineoplastic agents
|x Therapeutic use.
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| 650 |
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0 |
|a Dihydropyridine
|x Therapeutic use.
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| 700 |
1 |
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|a Bhat, Mashooq Ahmad,
|e editor.
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| 700 |
1 |
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|a Rehman. Muneeb U.,
|e editor.
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| 700 |
1 |
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|a Verma, Amita,
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|z 9780443153044
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| 776 |
0 |
8 |
|i Print version:
|z 0443190941
|z 9780443190940
|w (OCoLC)1360286365
|
| 856 |
4 |
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|u https://colorado.idm.oclc.org/login?url=https://www.sciencedirect.com/science/book/9780443190940
|z Full Text (via ScienceDirect)
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| 915 |
|
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|a 7
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| 956 |
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|a ScienceDirect ebooks
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| 956 |
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|b ScienceDirect All Books
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| 998 |
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|b Added to collection elsevier.ebooks
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| 994 |
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|a 92
|b COD
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|i 671adab6-803b-4aea-a648-90f4a67acead
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| 952 |
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f |
|p Can circulate
|a University of Colorado Boulder
|b Online
|c Online
|d Online
|e RS431.A64 D54 2023
|h Library of Congress classification
|i web
|
