In silico methods for predicting drug toxicity / edited by Emilio Benfenati.

This detailed volume explores in silico methods for pharmaceutical toxicity by combining the theoretical advanced research with the practical application of the tools. Beginning with a section covering sophisticated models addressing the binding to receptors, pharmacokinetics and adsorption, metabol...

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Bibliographic Details
Online Access: Full Text (via Springer)
Other Authors: Benfenati, Emilio (Editor)
Format: Electronic eBook
Language:English
Published: New York, NY : Humana Press, 2016.
Series:Methods in molecular biology (Clifton, N.J.) ; v. 1425.
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Description
Summary:This detailed volume explores in silico methods for pharmaceutical toxicity by combining the theoretical advanced research with the practical application of the tools. Beginning with a section covering sophisticated models addressing the binding to receptors, pharmacokinetics and adsorption, metabolism, distribution, and excretion, the book continues with chapters delving into models for specific toxicological and ecotoxicological endpoints, as well as broad views of the main initiatives and new perspectives which will very likely improve our way of modelling pharmaceuticals. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice that is key for achieving successful research results. Authoritative and practical, In Silico Methods for Predicting Drug Toxicity offers the advantage of incorporating data and knowledge from different fields, such as chemistry, biology, -omics, and pharmacology, to achieve goals in this vital area of research.
Physical Description:1 online resource (xi, 534 pages) : illustrations (some color)
Bibliography:Includes bibliographical references and index.
ISBN:9781493936090
1493936093
1493936077
9781493936076
ISSN:1940-6029 ;
Source of Description, Etc. Note:Online resource; title from PDF title page (SpringerLink, viewed June 23, 2016).