Thyroid hormone nuclear receptor : methods and protocols / edited by Michelina Plateroti, Jacques Samarut.
This volume aims to detail the advances in the field of Thyroid hormones (THs), namely T3 and T4, and their nuclear receptor TRs from a conceptual and methodological point of view. Chapters guide readers through a general introduction, TR's engineered mice, human genetics of TRs, control of the...
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Full Text (via Springer) |
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| Other Authors: | , |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
New York :
Humana Press : Springer,
[2018]
|
| Series: | Methods in molecular biology (Clifton, N.J.) ;
v. 1801. |
| Subjects: |
MARC
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| 245 | 0 | 0 | |a Thyroid hormone nuclear receptor : |b methods and protocols / |c edited by Michelina Plateroti, Jacques Samarut. |
| 264 | 1 | |a New York : |b Humana Press : |b Springer, |c [2018] | |
| 264 | 4 | |c ©2018 | |
| 300 | |a 1 online resource (xii, 300 pages) : |b illustrations (some color) | ||
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| 490 | 1 | |a Methods in molecular biology ; |v v. 1801 | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Online resource; title from PDF title page (SpringerProtocol viewed June 13, 2018). | |
| 520 | |a This volume aims to detail the advances in the field of Thyroid hormones (THs), namely T3 and T4, and their nuclear receptor TRs from a conceptual and methodological point of view. Chapters guide readers through a general introduction, TR's engineered mice, human genetics of TRs, control of the hypothalamus-pituitary-thyroid (HPT) axis, the relevance of the local THs production and metabolism and pathological consequences of TH/TR alterations. Non-mammalian models are also presented and discussed. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Thyroid Hormone Nuclear Receptor: Methods and Protocols aims to ensure successful results in the further study of this vital field. | ||
| 505 | 0 | |a Thyroid Hormones and Derivatives - Endogenous Thyroid Hormones and their Targets Josef Köhrle 10. Protocols for Studying how Thyroid Hormone Receptors Trigger Adaptive Thermogenesis in Mice Karine Gauthier 11. Pharmacological Inhibition of Lysosomal Activity as a Method For Monitoring Thyroid Hormone-induced Autophagic Flux in Mammalian Cells in vitro Jin Zhou, Rohit A. Sinha, Ronny Lesmana, Winifred WY. Yau, and Paul M. Yen 12. Analysis of Physiological Responses to Thyroid Hormones and their Receptors in Bone J.H. Duncan Bassett and Graham R. Williams 13. Evaluating the Hypothalamic-Pituitary-Thyroid (HPT) Axis in Mice FE Wondisford 14. Thyroid Hormone Action: The p43 Mitochondrial Pathway Chantal Wrutniak-Cabello, François Casas, and Gérard Cabello 15. Evaluating thyroid Disrupting Chemicals in vivo using Xenopus laevis Bilal B. Mughal, Barbara A Demeneix, and Jean-Baptiste Fini 16. | |
| 650 | 0 | |a Thyroid hormones. | |
| 650 | 0 | |a Molecular biology. | |
| 650 | 7 | |a Molecular biology |2 fast | |
| 650 | 7 | |a Thyroid hormones |2 fast | |
| 655 | 7 | |a Laboratory manuals |2 fast | |
| 700 | 1 | |a Plateroti, Michelina, |e editor. | |
| 700 | 1 | |a Samarut, Jacques, |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Thyroid hormone nuclear receptor. |z 9781493979011 |
| 830 | 0 | |a Methods in molecular biology (Clifton, N.J.) ; |v v. 1801. |x 1064-3745 | |
| 856 | 4 | 0 | |u https://colorado.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-1-4939-7902-8 |z Full Text (via Springer) |
| 880 | 0 | 0 | |6 505-00/(S |t Thyroid hormone receptors : several players for one hormone and multiple functions / |r Jacques Samarut and Michelina Plateroti -- |t Two protocols to study the interactions of thyroid hormone receptors with other proteins and chromatin / |r Wenyue Guan, Romain Guyot, and Frédéric Flamant -- |t Expression analysis of genes regulated by thyroid hormone in neural cells / |r Juan Bernal and Beatriz Morte -- |t In vitro approaches to identify thyroid hormone receptor-dependent transcriptional response / |r Maria Sirakov and Michelina Plateroti -- |t Posttranslational modification of thyroid hormone nuclear receptor by phosphorylation / |r Yan-Yun Liu and Gregory A. Brent -- |t Posttranslational modification of thyroid hormone nuclear receptor by sumoylation / |r Yan-Yun Liu and Gregory A. Brent -- |t Demonstration of the receptor site for thyroid hormone on integrin αvβ3 / |r Hung-Yun Lin, Shaker A. Mousa, and Paul J. Davis -- |t Deiodinase trio and thyroid hormone signaling / |r Antonio C. Bianco and Rodrigo R. da Conceição -- |t Thyroid hormones and derivatives : endogenous thyroid hormones and their targets / |r Josef Köhrle -- |t Protocols for studying how thyroid hormone receptors trigger adaptive thermogenesis in mice / |r Karine Gauthier -- |t Pharmacological inhibition of lysosomal activity as a method for monitoring thyroid hormone-induced autophagic flux in mammalian cells in vitro / |r Jin Zhou, Rohit A. Sinha, Ronny Lesmana, Winifred W.Y. Yau, and Paul M. Yen -- |t Analysis of physiological responses to thyroid hormones and their receptors in bone / |r J.H. Duncan Bassett and Graham R. Williams -- |t Evaluating the hypothalamic-pituitary-thyroid (HPT) axis in mice / |r F.E. Wondisford -- |t Thyroid hormone action : the p43 mitochondrial pathway / |r Chantal Wrutniak-Cabello, François Casas, and Gérard Cabello -- |t Evaluating thyroid disrupting chemicals in vivo using Xenopus laevis / |r Bilal B. Mughal, Barbara A. Demeneix, and Jean-Baptiste Fini -- |t Quantification of thyromimetic sobetirome concentration in biological tissue samples / |r Jordan Devereaux, Skylar J. Ferrara, and Thomas S. Scanlan -- |t Analysis of thyroid tumorigenesis in xenograft mouse model / |r Xuguang Zhu and Sheue-Yann Cheng -- |t Human genetics of thyroid hormone receptor beta : resistance to thyroid hormone beta (RTHβ) / |r Theodora Pappa and Samuel Refetoff -- |t TRα mutations in human / |r C. Briet, Natacha Bouhours-Nouet, F. Illouz, D. Prunier-Mirebeau, and P. Rodien -- |t Role of thyroid hormone receptor in amphibian Development / |r Liezhen Fu, Luan Wen, and Yun-Bo Shi -- |t De novo transcriptomic approach to study thyroid hormone receptor action in non-mammalian models / |r Nicolas Buisine, Gwenneg Kerdivel, and Laurent M. Sachs -- |t Role of TRs in zebrafish development / |r Federica Marelli and Luca Persani. |
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