Determining the Molecular Mechanisms of Soluble TREM2 in Alzheimer's Disease / David Saeb.
The microglial surface protein Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) plays a critical role in mediating brain homeostasis and inflammatory responses in Alzheimer's disease (AD). The soluble form of TREM2 (sTREM2) exhibits neuroprotective effects in AD, though the underlying m...
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Format: | Thesis Electronic eBook |
Language: | English |
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Ann Arbor :
ProQuest Dissertations & Theses,
2024.
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