Determining the Molecular Mechanisms of Soluble TREM2 in Alzheimer's Disease / David Saeb.

The microglial surface protein Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) plays a critical role in mediating brain homeostasis and inflammatory responses in Alzheimer's disease (AD). The soluble form of TREM2 (sTREM2) exhibits neuroprotective effects in AD, though the underlying m...

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Main Author: Saeb, David (Author)
Format: Thesis Electronic eBook
Language:English
Published: Ann Arbor : ProQuest Dissertations & Theses, 2024.
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