Cardiac amyloidosis : diagnosis and treatment / Michele Emdin, Giuseppe Vergaro, Alberto Aimo, Marianna Fontana, editors.

Cardiac amyloidosis (CA) is caused by the accumulation of amyloid fibrils in the extracellular space of the myocardium, with clinical manifestations including conduction disturbances and heart failure. CA has traditionally been considered a rare disease, lacking effective therapies and with a poor p...

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Bibliographic Details
Online Access: Full Text (via Springer)
Other Authors: Emdin, Michele (Editor), Vergaro, Giuseppe (Editor), Aimo, Alberto (Editor), Fontana, Marianna (Editor)
Format: eBook
Language:English
Published: Cham : Springer, 2024.
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Table of Contents:
  • 1. Tribute to Claudio Rapezzi
  • 2. Giampaolo Merlini and the Pavia School
  • 3. A brief history of amyloidosis
  • 4. Pathophysiology, classification and epidemiology of amyloidosis
  • 5. Amyloid light chain (AL) amyloidosis
  • 6. Hereditary transthyretin amyloidosis
  • 7. Wild-type ATTR amyloidosis
  • 8. Electrocardiographic patterns
  • 9. Echocardiography: a gatekeeper to diagnosis
  • 10. Cardiovascular magnetic resonance: characterization of myocardial involvement
  • 11. Biomarkers: monoclonal protein and indicators of cardiac damage
  • 12. Plasma transthyretin and its ligands
  • 13. Cardiac Scintigraphy with Bone-Avid Tracers - Old and New Applications
  • 14. PET-CT: a tool for etiological diagnosis
  • 15. The role of tissue biopsy: identification of the amyloid precursor and beyond
  • 16. From red flags to diagnosis
  • 17. Risk prediction and follow-up
  • 18. Differential diagnoses in clinical mimics
  • 19. Applications of Artificial Intelligence in Amyloidosis
  • 20. Treatment of amyloid light-chain amyloidosis
  • 21. Treatment of ATTR amyloidosis: from stabilizers to gene-editing
  • 22. Treatment of cardiac complications
  • 23. Monitoring disease progression and response to disease-modifying treatments
  • 24. Cardiac amyloidosis: open issues and future perspectives.