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|a E 1.99:1545687
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|a E 1.99:1545687
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|a Transforming Biological Science and Biomedical Practice
|h [electronic resource]
|
260 |
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|a Washington, D.C. :
|b United States. Department of Energy. Office of Basic Energy Sciences ;
|a Oak Ridge, Tenn. :
|b distributed by the Office of Scientific and Technical Information, U.S. Department of Energy,
|c 2018.
|
300 |
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|a 1 p. :
|b digital, PDF file.
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|a text
|b txt
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|a online resource
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|a Published through SciTech Connect.
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|a 06/01/2018.
|
500 |
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|a None, None.
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3 |
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|a Opioid overdoses killed more than 50,000 people in the U.S. in 2016, reaching epidemic proportions. New opioid drugs that suppress pain but are neither addictive nor likely to cause overdose deaths are now in the pharmaceutical pipeline, the result of decades of research into how medicines attach to and communicate with the body's cells. Critical to that research was a new method of determining the structure of large biological molecules, using extremely powerful beams of X-rays developed and supported at shared research facilities by the Basic Energy Sciences (BES) office of DOE. Such X-ray studies are now central to new drug development: the BES facilities are used by the pharmaceutical industry to screen most new drug candidates.
|
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|a Basic Biological Sciences.
|2 edbsc.
|
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|a Applied Life Sciences.
|2 edbsc.
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|a United States.
|b Department of Energy.
|b Office of Science.
|4 res.
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|a United States.
|b Department of Energy.
|b Office of Basic Energy Sciences.
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|a United States.
|b Department of Energy.
|b Office of Scientific and Technical Information.
|4 dst.
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|u http://www.osti.gov/scitech/biblio/1545687
|z Full Text (via OSTI)
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|a .b107967972
|b 10-03-19
|c 10-03-19
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|a University of Colorado Boulder
|b Online
|c Online
|d Online
|e E 1.99:1545687
|h Superintendent of Documents classification
|i web
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