Current advances in the science of osteosarcoma [electronic resource] : research perspectives: tumor biology, organ microenvironment, potential new therapeutic targets, and canine models / Eugenie S. Kleinerman, Richard Gorlick, editors.

This thoroughly revised second edition is an up-to-date overview of the new advances in the knowledge of the basic science in sarcoma and osteosarcoma. It features detailed, in-depth discussions of microRNAs in osteosarcoma, historical perspectives of chemotherapy in the treatment of the disease, tu...

Full description

Saved in:
Bibliographic Details
Online Access: Full Text (via Springer)
Other Authors: Kleinerman, Eugenie, Gorlick, Richard
Other title:Tumor biology, organ microenvironment, potential new therapeutic targets, and canine models.
Format: Electronic eBook
Language:English
Published: Cham, Switzerland : Springer, 2020.
Edition:Second edition.
Series:Advances in experimental medicine and biology ; v. 1258.
Subjects:
Table of Contents:
  • The genomic complexity of osteosarcoma and its implication for preclinical and clinical targeted therapies
  • Genomics and the Immune Landscape of Osteosarcoma
  • RECQ DNA Helicases and Osteosarcoma
  • Targeting the Cancer Epigenome with Histone Deacetylase Inhibitors in Osteosarcoma
  • Oncolytic viruses and their potential as a therapeutic opportunity in Osteosarcoma
  • Applying Osteosarcoma Immunology to Understand Disease Progression and Assess immunotherapeutic Response
  • Targetable intercellular signaling pathways facilitate lung colonization in osteosarcoma
  • Wnt Signaling in Osteosarcoma
  • Receptor Tyrosine Kinases in Osteosarcoma: 2019 update
  • The Role of ALDH in the Metastatic Potential of Osteosarcoma Cells and Potential ALDH Targets
  • Autophagy in OS
  • Fas signaling as a potential target for the treatment of osteosarcoma metastasis in the lungs
  • Exosomes: Dynamic Mediators of Extracellular Communication in the Tumor Microenvironment
  • Comparative Immunology and Immunotherapy of Canine Osteosarcoma
  • Index.