Micro-fluidic (Lab-on the- Chip) PCR Array Cartridge for Biological Screening in a Hand Held Device [electronic resource] : FInal Report for CRADA no 264. PNNL-T2-258-RU with CombiMatrix Corp.
Lab-on-a-chip; Nucleic Acid Detection Technology; Bio-agent Detection.
Saved in:
| Online Access: |
Online Access |
|---|---|
| Corporate Author: | |
| Format: | Government Document Electronic eBook |
| Language: | English |
| Published: |
Washington, D.C : Oak Ridge, Tenn. :
United States. Dept. of Energy ; distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy,
2010.
|
| Subjects: |
MARC
| LEADER | 00000nam a22000003u 4500 | ||
|---|---|---|---|
| 001 | b7069511 | ||
| 003 | CoU | ||
| 005 | 20110504000000.0 | ||
| 006 | m d f | ||
| 007 | cr ||||||||||| | ||
| 008 | 120331e20101031dcu ot f0|||||eng|d | ||
| 035 | |a (TOE)ost1008257 | ||
| 035 | |a (TOE)1008257 | ||
| 040 | |a TOE |c TOE | ||
| 049 | |a GDWR | ||
| 072 | 7 | |a 59 |2 edbsc | |
| 072 | 7 | |a 60 |2 edbsc | |
| 086 | 0 | |a E 1.99:pnnl-19914 | |
| 086 | 0 | |a E 1.99:pnnl-19914 | |
| 088 | |a pnnl-19914 | ||
| 245 | 0 | 0 | |a Micro-fluidic (Lab-on the- Chip) PCR Array Cartridge for Biological Screening in a Hand Held Device |h [electronic resource] : |b FInal Report for CRADA no 264. PNNL-T2-258-RU with CombiMatrix Corp. |
| 260 | |a Washington, D.C : |b United States. Dept. of Energy ; |a Oak Ridge, Tenn. : |b distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, |c 2010. | ||
| 300 | |a PDFN. | ||
| 336 | |a text |b txt |2 rdacontent. | ||
| 337 | |a computer |b c |2 rdamedia. | ||
| 338 | |a online resource |b cr |2 rdacarrier. | ||
| 500 | |a Published through the Information Bridge: DOE Scientific and Technical Information. | ||
| 500 | |a 10/31/2010. | ||
| 500 | |a "pnnl-19914" | ||
| 500 | |a "NN4006010" | ||
| 500 | |a Rainina, Evguenia I. | ||
| 520 | 3 | |a The worldwide emergence of both new and old diseases resulting from human expansion and also human and materials mobility has and will continue to place stress on both medical and clinical diagnostics. The classical approach to bioagents detection involves the use of differential metabolic assays to determine species type in the case of most bacteria, or the use of cell culture and electron microscopy to diagnose viruses and some bacteria that are intracellular parasites. The long-term goal in bioagent detection is to develop a hand-held instrument featuring disposable cartridges which contain all the necessary reagents, reaction chambers, waste chambers, and micro-fluidics to extract, concentrate, amplify, and analyze nucleic acids. This GIPP project began development of a sensory platform using nucleic-acid based probes. Although research was not completed, initial findings indicated that an advanced sensing device could theoretically be built on a DNA/RNA-based technology platform. | |
| 520 | 0 | |a Lab-on-a-chip; Nucleic Acid Detection Technology; Bio-agent Detection. | |
| 536 | |b AC05-76RL01830. | ||
| 650 | 7 | |a Cell Cultures. |2 local. | |
| 650 | 7 | |a Bacteria. |2 local. | |
| 650 | 7 | |a Diseases. |2 local. | |
| 650 | 7 | |a Detection. |2 local. | |
| 650 | 7 | |a Electron Microscopy. |2 local. | |
| 650 | 7 | |a Parasites. |2 local. | |
| 650 | 7 | |a Wastes. |2 local. | |
| 650 | 7 | |a Viruses. |2 local. | |
| 650 | 7 | |a Nucleic Acids. |2 local. | |
| 650 | 7 | |a Applied Life Sciences. |2 edbsc. | |
| 650 | 7 | |a Basic Biological Sciences. |2 edbsc. | |
| 710 | 2 | |a Pacific Northwest National Laboratory (U.S.). |4 res. | |
| 710 | 1 | |a United States. |b Department of Energy. |4 spn. | |
| 710 | 1 | |a United States. |b Department of Energy. |b Office of Scientific and Technical Information. |4 dst. | |
| 856 | 4 | 0 | |u http://www.osti.gov/servlets/purl/1008257-FJK5GN/ |z Online Access |
| 907 | |a .b70695118 |b 03-07-23 |c 04-04-12 | ||
| 998 | |a web |b 04-04-12 |c f |d m |e p |f eng |g dcu |h 0 |i 1 | ||
| 956 | |a Information bridge | ||
| 999 | f | f | |i c5d50aae-af3f-5746-9f0f-94d18f9bf126 |s 16349d79-723d-5c93-b820-c0e757c9fe4b |
| 952 | f | f | |p Can circulate |a University of Colorado Boulder |b Online |c Online |d Online |e E 1.99:pnnl-19914 |h Superintendent of Documents classification |i web |n 1 |