One hundred years of chromosome research and what remains to be learned / by A. Lima-de-Faria.
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Full Text (via Springer) |
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| Format: | eBook |
| Language: | English |
| Published: |
Dordrecht ; Boston :
Kluwer Academic Publishers,
2003.
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| Subjects: |
Table of Contents:
- Nine Periods of Chromosome Research: 1795 to 2010
- First Period 1795-1850 The precursors: Better microscopes allowed reaching the cell level
- Second Period 1850-1900 The pioneers: The discovery of the chromosome was a by-product of microbiology
- Third Period 1900-1930 The era of abstract genetics: Order in embryonic development led to the finding of order in inheritance
- Fourth Period 1930-1950 The impact of physics and chemistry on genetics: World War II encouraged the development of microbial genetics
- Fifth Period 1950-1970 Radioisotopes and electron microscopy became a most fruitful combination: Molecular biology received its main impulse from disciplines outside genetics
- Sixth Period 1970-1980 The mechanisms of cancer and of development were sought at the DNA level: Biotechnology emerged as a new field as genetics created its own weapons
- Seventh Period 1980-1990 Neurobiology reached the molecular level: Artificial chromosomes and gene therapy became a reality
- Eighth Period 1990-2001 The genome of humans and of other organisms was sequenced: The age of multilaboratory collaboration was established
- Ninth Period 2001-2010 The post-genome era: The task that lies ahead
- The Technology that Allowed the Study of the Chromosome: 1900 to 2001
- From staining methods to DNA sequencing
- In Search of the Eukaryotic Chromosome
- Main stages in the discovery of the cell's structure and function
- The nucleus versus the cytoplasm. Which was most important?