Determination of beta-blockers in biological material / edited by V. Marko ; general editor, R.A. de Zeeuw.
This is the third volume of a sub-series entitled Evaluation of Analytical Methods in Biological Systems. (The first two were Analysis of Biogenic Amines edited by G.B. Baker and R.T. Coutts, and Hazardous Metals in Human Toxicology edited by A. Vercruysse). This latest volume addresses beta-blocker...
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Full Text (via ScienceDirect) |
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| Other Authors: | , |
| Format: | eBook |
| Language: | English |
| Published: |
Amsterdam :
Elsevier,
1989.
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| Series: | Techniques and instrumentation in analytical chemistry ;
v. 4, pt. C. |
| Subjects: |
MARC
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| 245 | 0 | 0 | |a Determination of beta-blockers in biological material / |c edited by V. Marko ; general editor, R.A. de Zeeuw. |
| 264 | 1 | |a Amsterdam : |b Elsevier, |c 1989. | |
| 300 | |a 1 online resource (xiv, 320 pages) : |b illustrations. | ||
| 336 | |a text |b txt |2 rdacontent. | ||
| 337 | |a computer |b c |2 rdamedia. | ||
| 338 | |a online resource |b cr |2 rdacarrier. | ||
| 490 | 1 | |a Techniques and instrumentation in analytical chemistry ; |v volume 4, part c. | |
| 504 | |a Includes bibliographical references and indexes. | ||
| 505 | 0 | |6 880-01 |a Front Cover; Determination of Beta-Blockers in Biological Material; Copyright Page; Table of Contents; List of contributors; PREFACE; INTRODUCTION; REFERENCES; CHAPTER 1. RECENT DEVELOPMENTS IN THE CLINICAL PHARMACOLOGY OF ß-BLOCKERS; 1.1 INTRODUCTION; 1.2 CLINICAL PHARMACOLOGY PROPERTIES; 1.3 THE PHARMACOKINETICS OF ß -ANTAGONISTS; REFERENCES; CHAPTER 2. CLINICAL PHARMACOKINETICS OF BETA-BLOCKERS; 2.1 INTRODUCTION; 2.2 BASIC INFORMATION ON PHYSICO-CHEMICAL PROPERTIES AND PHARMACOKINETICS OF BETA-BLOCKERS; 2.3 BLOOD LEVELS OF BETA-BLOCKERS. | |
| 505 | 8 | |a 2.4 correlation between pharmacokinetic and pharmacodynamic response2.5 elimination kinetics of beta-adrenoceptor blocking drugs; 2.6 chronopharmacokinetics of beta-blockers; 2.7 alterations in the pharmacokinetics of beta-blockers during chronic regimens; 2.8 polymorphic oxidation of beta-blockers; 2.9 stereoselective disposition of beta-blockers in man; 2.10 inter- and intra-subject variability of the pharmacokinetics of beta-bockers; 2.11 pharmacokinetics of beta-blockers in pregnancy; 2.12 placental transfer of beta-blockers; 2.13 excretion of beta-blockers into human breast milk. | |
| 505 | 8 | |a 2.14 effect of food on the plasma level of beta-blockers2.15 pharmacokinetics of beta-blockers in elderly subjects; 2.16 effect of disease on the clinical pharmacokinetics of betablockers; 2.17 interaction of drugs with the pharmacokinetics of beta-blockers; 2.18 pharmacokinetics op slow-release formulations; references; chapter 3. sample pretreatment in the determination of beta-blockers in biological fluids; 3.1 introduction; 3.2 structure of beta-blockers; 3.3 biological fluids; 3.4 preparation of the analytical sample; 3.5 future perspectives; references. | |
| 505 | 8 | |a CHAPTER 4. DETERMINATION OF BETA-BLOCKERS BY OPTICAL METHODS4.1 INTRODUCTION; 4.2 SPECTROPHOTOMETRIC PROPERTIES OF BETA-BLOCKERS; 4.3 OPTICAL METHODS; 4.4 VALIDITY OF SPECTROFLUOROMETRY; REFERENCES; CHAPTER 5.1 GAS-LIQUID CHROMATOGRAPHY OF BETA-BLOCKERS; 5.1.1 INTRODUCTION; 5.1.2. DERIVATIZATION OF ß-BLOCKERS FOR GAS CHROMATOGRAPHY; 5.1.3 ß-BLOCKERS AND THE GAS-CHROMATOGRAPHIC COLUMN; 5.1.4. DETECTION; 5.1.5. CHOOSING COLUMN DIMENSIONS; 5.1.6 SAMPLE INTRODUCTION; 5.1.7 COMPARISON OF DIFFERENT GLC METHODS; ACKNOWLEDGEMENTS; REFERENCES. | |
| 520 | |a This is the third volume of a sub-series entitled Evaluation of Analytical Methods in Biological Systems. (The first two were Analysis of Biogenic Amines edited by G.B. Baker and R.T. Coutts, and Hazardous Metals in Human Toxicology edited by A. Vercruysse). This latest volume addresses beta-blockers - an area of research for which a Nobel Prize in Medicine was awarded in 1988. It provides an up-to-date and comprehensive coverage of the theory and practice of the determination of beta-blockers in biological material. Two main fields of research are dealt with in this book: analytical chemistry. | ||
| 588 | 0 | |a Print version record. | |
| 650 | 0 | |a Biochemistry |x Technique. |0 http://id.loc.gov/authorities/subjects/sh85014172. | |
| 650 | 7 | |a Biochemistry |x Technique. |2 fast |0 (OCoLC)fst00831987. | |
| 700 | 1 | |a Zeeuw, R. A. de, |e editor. | |
| 700 | 1 | |a Marko, V., |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Evaluation of analytical methods in biological systems. . Part C, Determination of beta-blockers in biological material |z 0444873058 |w (OCoLC)867134543. |
| 830 | 0 | |a Techniques and instrumentation in analytical chemistry ; |v v. 4, pt. C. |0 http://id.loc.gov/authorities/names/n42010107. | |
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| 880 | 0 | |6 505-01/(S |a CHAPTER 5.2 HPLC DETERMINATION OF BETA-ADRENERGIC BLOCKERS IN BIOLOGICAL FLUIDS5.2.1 INTRODUCTION; 5.2.2 METHODS FOR QUANTITATION OF INDIVIDUAL BETA BLOCKERS; 5.2.3 DISCUSSION; 5.2.4 ACKNOWLEDGEMENTS; 5.2.4 REFERENCES; CHAPTER 5.3 THIN-LAYER CHROMATOGRAPHY; 5.3.1 INTRODUCTION; 5.3.2 DETERMINATION OF ß-ADRENOCEPTOR ANTAGONISTS BY READING NATIVE FLUORESCENCE ON TLC PLATES; 5.3.3 DETERMINATION OF CARTEOLOL AND ITS METABOLITES BY UV ABSORBANCE; 5.3.4 DETERMINATION OF (β-ADRENOCEPTOR ANTAGONISTS BY THE FORMATION OF EDTN-DERIVATIVES; REFERENCES. | |
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