Neurodegenerative diseases / Donald B. Calne.

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Bibliographic Details
Other Authors: Calne, Donald B. (Donald Brian)
Format: Book
Language:English
Published: Philadelphia : W.B. Saunders Co., ©1994.
Subjects:

MARC

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245 0 0 |a Neurodegenerative diseases /  |c Donald B. Calne. 
260 |a Philadelphia :  |b W.B. Saunders Co.,  |c ©1994. 
300 |a xviii, 954 pages :  |b illustrations (some color) ;  |c 29 cm. 
336 |a text  |b txt  |2 rdacontent. 
337 |a unmediated  |b n  |2 rdamedia. 
338 |a volume  |b nc  |2 rdacarrier. 
504 |a Includes bibliographical references and index. 
505 0 |a Basic sciences -- Structures of neurons in the aging nervous system -- Vulnerability of specific neurons to aging -- Molecular biology of aging in the nervous system: a synopsis of the levels of mechanisms -- Lewy bodies -- Neurofibrillary tangles -- Beta-protein fibrillogenesis and neuritic plaques -- Neurotransmitters in neurodegeneration -- Neurotransmitter receptors in neurodegeneration -- Tissue culture models of neurodegeneration -- Free radicals, oxidative stress and neurodegeneration -- Glutamate excitotoxicity as a possible pathogenetic mechanism in chronic neurodegeneration -- Growth factors and neurodegeneration -- Mitochondrial disturbances in neurodegeneration -- Susceptibility to neurotoxins -- Organic neurotoxicants -- Inorganic neurotoxins in dementia caused by neurodegeneration -- Inorganic neurotoxins in neurodegenerative disorders without primary dementia -- Neurodegeneration and the immune system. (cont) Infectious and noninfectious amyloidoses of the brain: systemic amyloidoses as predictive models in transmissible and nontransmissible amloidotic neurodegeneration of Creutzfeldt-Jakob disease and aging brain and Alzheimer's disease -- Bacteria and neurodegeneration -- Molecular genetic approaches to neurodegenerative disease -- Compensatory mechanisms in central neurodegenerative disease -- Animal models of neurodegenerative disease -- Clinical sciences -- Normal aging of the nervous system -- Epidemiological overview of amyotrophic lateral sclerosis, Parkinson's disease and dementia of the Alzheimer type -- Positron emission tomography -- Magnetic resonance imaging in neurodegenerative diseases -- Amyotrophic lateral sclerosis -- Pathogenic mechanisms in amyotrophic lateral sclerosis and other motor neuron disorders -- Clinical electrophysiology of amyotrophic lateral sclerosis -- Natural history nd clinical features of amyotrophic lateral sclerosis and related motor neuron diseases -- Treatment of amyotrophic lateral sclerosis. (cont) Parkinson's disease -- Pathology of Parkinson's disease -- Clinical features and natural history of Parkinson's disease (special consideration of aging) -- Treatment of Parkinson's disease -- Dementia of Alzheimer's type -- Pathology of Alzheimer's disease -- Cognitive changes in dementia of the Alzheimer type -- Clinical features and natural history of Alzheimer's disease -- Rational therapeutic strategies for Alzheimer's disease -- Other eurodegenerative disorders -- Wilson's disease (progressive hepatolenticular degeneration) -- Huntington's disease -- Idiopathic torsion dystonia -- Essential tremor -- Shy-drager syndrome (and multiple system atrophy) -- Progressive supranuclear palsy -- Cerebellar degenerations -- Hallervorden-Spatz syndrome: an iron-storage disease -- Sudanophilic (orthochromatic) leukodystrophies -- Transmissible human spongiform encephalopathy (infectious cerebral myloidosis): Creutzfeldt-Jakob disease, Gerstmann-Straussler-Scheinker syndrome and Kuru -- Cortical-basal ganglionic degeneration -- Guam neurodegeneration -- Rare neurodegenerative disorders. 
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650 0 |a Nervous system  |x Degeneration.  |0 http://id.loc.gov/authorities/subjects/sh85090923. 
650 2 |a Nerve Degeneration. 
650 2 |a Nervous System  |x physiology. 
650 2 |a Nervous System  |x physiopathology. 
700 1 |a Calne, Donald B.  |q (Donald Brian)  |0 http://id.loc.gov/authorities/names/n80026025  |1 http://isni.org/isni/0000000385761724. 
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